- Djimon Hounsou
- Â Black Panther / ... 6 episodes, 2010
- Jill Scott
- Â Storm / ... 6 episodes, 2010
- Carl Lumbly
- Â Uncle S'Yan / ... 6 episodes, 2010
- Stephen Stanton
- Â Klaw / ... 6 episodes, 2010
- Kerry Washington
- Â Princess Shuri / ... 5 episodes, 2010
- Alfre Woodard
- Â Dondi Reece / ... 5 episodes, 2010
- David Busch
- Â Everett Ross / ... 5 episodes, 2010
- JB Blanc
- Â Batroc the Leaper / ... 5 episodes, 2010
- Phil Morris
- Â W'Kabi / ... 5 episodes, 2010
- Rick D. Wasserman
- Â Igor Stancheck / ... 5 episodes, 2010
- Vanessa Marshall
- Â Female Cannibal / ... 5 episodes, 2010
- Peter Lurie
- Â Juggernaut / ... 5 episodes, 2010
- Georgette Perna
- Â Female Medic / ... 4 episodes, 2010
- Kevin Michael Richardson
- Â Wolverine / ... 4 episodes, 2010
- Phil LaMarr
- Â T'Shan / ... 3 episodes, 2010
- Nolan North
- Â Cyclops / ... 2 episodes, 2010
- Jonathan Adams
- Â Citizen / ... 2 episodes, 2010
- Taye Diggs
- Â Historical Panther #2 1 episode, 2010
- Stan Lee
- Â General Wallace 1 episode, 2010
- Adrian Pasdar
- Â Captain America 1 episode, 2010
- Earl White
- Â Warrior #1 / ... 1 episode, 2010
- Reginald Hudlin
- Â President 1 episode, 2010