- Colleen O'Shaughnessey
- Sora Takenouchi / Mrs. Mochizuki (voice)
- Cherami Leigh
- Biyomon / Maki Himekawa (voice)
- Robbie Daymond
- Joe Kido
- Cristina Valenzuela
- Meiko Mochizuki
- Johnny Yong Bosch
- T.K. Takaishi
- Vic Mignogna
- Matt Ishida
- Natsuki Hanae
- Taichi Yagami
- Kate Higgins
- Gatomon / Angewomon / Nyaromon / Meicoomon / Meicrackmon Vicious Mode / Raguelmon (voice)
- Kirk Thornton
- Gabumon / Garurumon / WereGarurumon / MetalGarurumon / Tsunomon / Omnimon / Additional Voices (voice)
- John Eric Bentley
- Additional Voices
- Kyle Hebert
- Greymon / MetalGreymon / WarGreymon / Omnimon (voice)
- Mona Marshall
- Izzy Izumi / Garudamon / Pheonixmon / Additional Voices (voice)
- Tara Sands
- Kari Kamiya / Homeostasis (voice)
- Takahiro Sakurai
- Tentomon / Kabuterimon / AtlurKabuterimon / HerakleKabuterimon (voice)
- Aaron LaPlante
- Hackmon / Jesmon / Professor Mochizuki (voice)
- Junko Takeuchi
- Gomamon / Ikkakumon / Zudomon / Vikemon (voice)
- Doug Erholtz
- Daigo Nishijima / Koromon / Additional Voices (voice)
- Yoshimasa Hosoya
- Yamato Ishida
- Jun'ya Enoki
- Takeru Takaishi
- Philece Sampler
- Mimi Tachikawa
- Joshua Seth
- Tai Kamiya
- Hiroaki Hirata
- Dark Gennai
- Dorothy Elias-Fahn
- Yuuko Kamiya / Lillymon / Rosemon (voice) (as Dorothy Fahn)
- Mao Ichimichi
- Hikari Yagami / Homeostasis (voice)
- Laura Summer
- Patamon
- Dave Mallow
- (credit only)
- Shunsuke Takeuchi
- Huckmon / Jesmon (voice)
- Yûko Kaida
- Maki Himekawa
- Jeff Nimoy
- Tentomon / Kabuterimon / MegaKabuterimon / HerculesKabuterimon / Dark Gennai (voice)
- Tom Fahn
- Agumon
- Mutsumi Tamura
- Koushiro Izumi
- Shin'ya Takahashi
- (voice)
- Chika Sakamoto
- Koromon / Agumon / Greymon / MetalGreymon / WarGreymon (voice)
- Yutaka Aoyama
- Professor Mochizuki
- Melodee Spevack
- Birdramon
- Suzuko Mimori
- Sora Takenouchi
- R. Martin Klein
- Gomamon / Ikkakumon / Additional Voices (voice) (as Bob Klein)
- Hitomi Yoshida
- Mimi Tachikawa / Mrs. Mochizuki (voice)
- Junya Ikeda
- Joe Kido
- Miwa Matsumoto
- Patamon / Angemon / HolyAngemon / Seraphimon (voice)
- Mayumi Yamaguchi
- Gabumon / Garurumon / WereGarurumon / MetalGarurumon (voice)
- Yukiko Morishita
- Meicoomon / Meicrackmon Vicious Mode / Raguelmon (voice)
- Atori Shigematsu
- Piyomon / Birdramon / Garudamon / Hououmon / Yuuko Yagami (voice) (as Katori Shigematsu)
- Miho Arakawa
- Meiko Mochizuki
- Kinoko Yamada
- Palmon / Togemon / Lilimon / Rosemon (voice)
- Yuka Tokumitsu
- Nyaromon / Tailmon / Angewomon (voice)
- Mari Devon
- Togemon
- Todd Haberkorn
- Digimon Emperor
- Jamieson Price
- Angemon / MagnaAngemon / Seraphimon / Additional Voices (voice) (uncredited)
- Michael Sorich
- Zudomon / Vikemon (voice) (uncredited)
