- Derek Waters
- Â Self - Host / ... 72 episodes, 2013-2019
- Bennie Arthur
- Â Various / ... 72 episodes, 2013-2019
- Craig Cackowski
- Â Various / ... 70 episodes, 2013-2019
- Maria Blasucci
- Â Various / ... 68 episodes, 2013-2019
- Mort Burke
- Â Various / ... 61 episodes, 2014-2019
- Michael Coleman
- Â Various / ... 60 episodes, 2013-2019
- Aasha Davis
- Â Various / ... 52 episodes, 2015-2019
- JT Palmer
- Â Various / ... 49 episodes, 2015-2019
- Tim Baltz
- Â Various 20 episodes, 2014-2016
- Greg Tuculescu
- Â Various / ... 19 episodes, 2015-2019
- Tymberlee Hill
- Â Various / ... 18 episodes, 2013-2018
- Jeremy J. Tutson
- Â Various 16 episodes, 2013-2014
- Craig Anstett
- Â Self - Narrator / ... 12 episodes, 2013-2019
- Rich Fulcher
- Â Self - Narrator / ... 12 episodes, 2013-2019
- Jack McBrayer
- Â Abraham Lincoln / ... 11 episodes, 2013-2019
- Steve Berg
- Â Self - Narrator / ... 9 episodes, 2013-2019
- Tony Hale
- Â Buster Keaton / ... 8 episodes, 2013-2019
- Mark Gagliardi
- Â Self - Narrator / ... 8 episodes, 2013-2019
- Paget Brewster
- Â Self - Narrator / ... 8 episodes, 2013-2019
- Jason Ritter
- Â Art Heist Investigator / ... 8 episodes, 2013-2018
- Eric Edelstein
- Â Self - Narrator / ... 8 episodes, 2013-2019
- Taran Killam
- Â Bobby Fischer / ... 8 episodes, 2013-2019
- Sarah Burns
- Â Various 8 episodes, 2013
- Michael Daniel Cassady
- Â Various 8 episodes, 2013-2016
- Adam Nee
- Â Various 8 episodes, 2013-2016
- Allan McLeod
- Â Self - Narrator 6 episodes, 2013-2019
- Duncan Trussell
- Â Self - Narrator 6 episodes, 2014-2019
- Amber Ruffin
- Â Self - Narrator / ... 6 episodes, 2014-2019
- Chris Parnell
- Â Benedict Arnold / ... 6 episodes, 2013-2019
- Colin Hanks
- Â Charles Dickens / ... 6 episodes, 2015-2019
- Joe Lo Truglio
- Â John Adams / ... 5 episodes, 2013-2016
- Martin Starr
- Â Abraham Lincoln / ... 5 episodes, 2013-2019
- Daryl J. Johnson
- Â Self - Narrator / ... 5 episodes, 2015-2019
- J.D. Ryznar
- Â Self - Narrator 5 episodes, 2014-2019
- Lyric Lewis
- Â Self - Narrator 4 episodes, 2016-2019
- Alison Rich
- Â Self - Narrator / ... 4 episodes, 2018-2019
- Tess Lynch
- Â Self - Narrator 4 episodes, 2015-2019
- Hillary Anne Matthews
- Â Self - Narrator / ... 4 episodes, 2016-2019
- Lucius Dillon
- Â Self - Narrator 4 episodes, 2013-2019
- Jerry O'Connell
- Â Thomas Jefferson / ... 4 episodes, 2014-2019
- Johnny Knoxville
- Â Johnny Cash / ... 4 episodes, 2014-2018
- Matt Gourley
- Â Self - Narrator / ... 4 episodes, 2013-2015
- Anais Fairweather
- Â Self - Narrator / ... 4 episodes, 2019
- Jack Black
- Â Elvis Presley / ... 4 episodes, 2013-2018
- Ken Marino
- Â Capt. James Cook / ... 4 episodes, 2013-2019
- Jen Kirkman
- Â Self - Narrator 4 episodes, 2013-2016
- David Koechner
- Â Diego Columbus / ... 4 episodes, 2015-2019
- Jayma Mays
- Â Abigail Adams / ... 4 episodes, 2014-2019
- David Wain
- Â Self - Narrator / ... 4 episodes, 2014-2019
- Seth Weitberg
- Â Self - Narrator / ... 4 episodes, 2013-2015
- Bob Odenkirk
- Â Richard Nixon / ... 4 episodes, 2013-2018
- Preston Flagg
- Â Self - Narrator / ... 4 episodes, 2013-2019
- Chris Romano
- Â Self - Narrator 4 episodes, 2013-2018
- Dan Cooley
- Â Don Mattingly / ... 4 episodes, 2013-2015
- Samuel Platt
- Â Aquaduct Worker / ... 3 episodes, 2015-2018
- Doug Anthony Jones
- Â Self - Narrator 3 episodes, 2016-2019
- Jon Gabrus
- Â Self - Narrator / ... 3 episodes, 2018-2019
- Mae Whitman
- Â Self - Narrator / ... 3 episodes, 2016-2019
- Busy Philipps
- Â Eleanor Roosevelt / ... 3 episodes, 2014-2018
- Kat Dennings
- Â Gertrude Harding / ... 3 episodes, 2015-2018
- Zach Gilford
- Â Ed Pulaski / ... 3 episodes, 2014-2019
- Paul Scheer
- Â Carl Sagan / ... 3 episodes, 2014-2018
- Jason Mantzoukas
- Â Eddie Aikau / ... 3 episodes, 2014-2018
- Alia Shawkat
- Â Alexander Hamilton / ... 3 episodes, 2014-2016
- Katie Nolan
- Â Self - Narrator 3 episodes, 2016-2019
- Jenny Slate
- Â Self - Narrator 3 episodes, 2013-2016
- Thomas Middleditch
- Â John Muir / ... 3 episodes, 2015-2019
- Michael Cera
- Â Andrew Jackson / ... 3 episodes, 2013-2016
- Josh Charles
- Â Alfred Kinsey / ... 3 episodes, 2016-2019
- Kirby Howell-Baptiste
- Â Self - Guest Host / ... 3 episodes, 2018-2019
- Suzi Barrett
- Â Self - Narrator 3 episodes, 2014-2019
- John Ennis
- Â John D. Rockefeller / ... 3 episodes, 2015-2018
- Ron Funches
- Â Herbert Muhammad / ... 3 episodes, 2014-2016
- Sugar Lyn Beard
- Â Catharine Fox / ... 3 episodes, 2016-2019
- Jake Johnson
- Â Boris Spassky / ... 3 episodes, 2013-2019
- Matt Besser
- Â Edwin Stanton / ... 3 episodes, 2013-2016
- Crissle West
- Â Self - Narrator 3 episodes, 2015-2018
- Samm Levine
- Â Fiorello LaGuardia / ... 3 episodes, 2015-2018
- Jesse Plemons
- Â Charles Ponzi / ... 3 episodes, 2014-2018
- Jaleel White
- Â Bass Reeves / ... 3 episodes, 2014-2018
- Justin Long
- Â Arno Penzias / ... 3 episodes, 2015-2019
- Vanessa Bayer
- Â Carrie Nation / ... 3 episodes, 2016-2019
- Aubrey Plaza
- Â Aaron Burr / ... 3 episodes, 2013-2019
- Drew Droege
- Â Self - Narrator 3 episodes, 2014-2019
- Kyle Kinane
- Â Self - Narrator 3 episodes, 2013-2016
- Jackie Michele Johnson
- Â Carol / ... 3 episodes, 2015-2019
- Stephen Merchant
- Â Abraham Lincoln / ... 3 episodes, 2013-2015
- Kyle Mooney
- Â Sam Patch / ... 3 episodes, 2014-2018
- Patton Oswalt
- Â Charles Sumner / ... 3 episodes, 2014-2016
- Vanessa Hudgens
- Â Joan of Arc / ... 3 episodes, 2018-2019
- Patrick Walsh
- Â Self - Narrator 3 episodes, 2014-2016
- Aaron Takahashi
- Â FBI Agent / ... 3 episodes, 2018-2019
- Lauren Lapkus
- Â Self - Narrator / ... 3 episodes, 2014-2016
- Thomas Lennon
- Â Jesse Marcel / ... 3 episodes, 2015-2019
- A.J. Culp
- Â Alice Roosevelt / ... 3 episodes, 2013-2019
- Ellie Culp
- Â Ethel Roosevelt / ... 3 episodes, 2015-2019
- David Sampen
- Â Journalist and World Traveler / ... 2 episodes, 2015-2018
- Tommy Blacha
- Â Self - Narrator 2 episodes, 2013
- John Lutz
- Â Self - Narrator 2 episodes, 2018-2019
- Emily Deschanel
- Â Babe Didrikson / ... 2 episodes, 2014-2019
- Natasha Leggero
- Â Elizabeth Bisland / ... 2 episodes, 2013-2015
- Juno Temple
- Â Marilyn Monroe / ... 2 episodes, 2014-2016
- John Lithgow
- Â George Washington / ... 2 episodes, 2014
- Carl Tart
- Â Self - Narrator 2 episodes, 2018-2019
- Georgia Hardstark
- Â Self - Narrator 2 episodes, 2013-2018
- Rob Huebel
-  Juan Francisco Treviño / ... 2 episodes, 2013-2015
- Lisa Bonet
- Â Mary Ellen Pleasant / ... 2 episodes, 2013-2014
- Mariah Iman Wilson
- Â Carrie Nation Voting Fangirl / ... 2 episodes, 2014-2016
- Josh Hartnett
- Â Clark Gable / ... 2 episodes, 2015-2019
- Claudia O'Doherty
- Â Self - Narrator 2 episodes, 2015-2018
- Jennie Pierson
- Â Self - Narrator 2 episodes, 2018-2019
- Rob Riggle
- Â J. Edgar Hoover / ... 2 episodes, 2013-2016
- Timm Sharp
- Â Billy the Kid / ... 2 episodes, 2013-2015
- Winona Ryder
- Â Mary Dyer / ... 2 episodes, 2013-2014
- Aidan Sussman
- Â Young Jim Abbott / ... 2 episodes, 2014-2015
- Da'Vone McDonald
- Â Big Bank Hank / ... 2 episodes, 2014-2015
- Allison Tolman
- Â Elizabeth Krebs / ... 2 episodes, 2016-2018
- Elijah Wood
- Â John Raines / ... 2 episodes, 2019
- Phil Hendrie
- Â Self - Narrator 2 episodes, 2014-2017
- Drew Pinsky
- Â Judge / ... 2 episodes, 2015-2019
- Jimmy O. Yang
- Â Genghis Khan / ... 2 episodes, 2018
- Terry Crews
- Â Donald 'Cinque' DeFreeze / ... 2 episodes, 2013-2014
- Jason Momoa
- Â Jean Lafitte / ... 2 episodes, 2014-2015
- Will Ferrell
- Â Roald Dahl / ... 2 episodes, 2015-2019
- Michael McKean
- Â Arthur Jell / ... 2 episodes, 2015-2016
- Kevin P. Farley
- Â Al Capone / ... 2 episodes, 2016-2018
- Steve Agee
- Â Lt. Colonel Harry Reeder / ... 2 episodes, 2018-2019
- Randall Park
- Â Jamukha / ... 2 episodes, 2018
- Lauren Sivan
- Â Barbara Walters / ... 2 episodes, 2015-2019
- Donald Faison
- Â Joe Louis / ... 2 episodes, 2015-2018
- Brendon Walsh
- Â Self - Narrator 2 episodes, 2015-2018
- Trace Lysette
- Â Elizabeth Eden / ... 2 episodes, 2016-2019
- Seth Rogen
- Â Victor Frankenstein / ... 2 episodes, 2018-2019
- Sheaun McKinney
- Â Lewis Swegles / ... 2 episodes, 2018
- Minka Kelly
- Â Florence Nightingale / ... 2 episodes, 2019
- Eric Filipkowski
- Â Abraham Lincoln 2 episodes, 2013-2016
- Courteney Cox
- Â Edith Wilson 2 episodes, 2014-2016
- Michaela Watkins
- Â Julia Child / ... 2 episodes, 2014-2016
- Rachel Bilson
- Â Constance Kopp / ... 2 episodes, 2016-2019
- Brian Tyree Henry
- Â Berry Gordy / ... 2 episodes, 2018-2019
- Evan Rachel Wood
- Â Deborah Sampson / ... 2 episodes, 2018-2019
- Brett Gelman
- Â Art Thief / ... 2 episodes, 2013-2014
- Miles Brown
- Â Louis Armstrong / ... 2 episodes, 2015-2018
- Brendan Sexton III
- Â Felix / ... 2 episodes, 2016-2018
- Horatio Sanz
- Â Alberto Bravo / ... 2 episodes, 2013-2015
- Jeremy Konner
- Â Henry Kissinger / ... 2 episodes, 2015
- Matt Walsh
- Â Joseph Pulitzer / ... 2 episodes, 2013-2014
- Ashley Johnson
- Â Elizabeth Cherry / ... 2 episodes, 2016-2018
- Steven Weber
- Â John Lomax / ... 2 episodes, 2019
- Richard Riehle
- Â James Roche / ... 2 episodes, 2013-2018
- Dave Grohl
- Â Hamilton Opponent / ... 2 episodes, 2013-2016
- Casey Wilson
- Â Dolley Madison / ... 2 episodes, 2013-2014
- Bobby Moynihan
- Â Grover Cleveland / ... 2 episodes, 2014-2019
- 'Weird Al' Yankovic
- Â Adolf Hitler / ... 2 episodes, 2014-2018
- Nicholas Rutherford
- Â Self - Narrator 2 episodes, 2014-2016
- Mike Still
- Â Self - Narrator 2 episodes, 2015-2016
- Jenny Johnson
- Â Self - Narrator 2 episodes, 2014-2016
- Gaius Charles
- Â Moses Fleetwood Walker / ... 2 episodes, 2015-2019
- Rob Corddry
- Â George Washington / ... 2 episodes, 2017-2018
- Tim Heidecker
- Â Cop / ... 2 episodes, 2013-2014
- Charlie Finn
- Â Cpt. 'Black Jack' Bonfield / ... 2 episodes, 2013-2016
- Callum Joyce
- Â Young Buster Keaton / ... 2 episodes, 2015-2016
- Nathan Fielder
- Â Bob Woodward / ... 2 episodes, 2013-2014
- Eris Baker
- Â Cindy Campbell / ... 2 episodes, 2018
- Kent Avenido
- Â Hawaiian / ... 2 episodes, 2014-2016
- Joseph Billingiere
- Â Various 2 episodes, 2013-2015
- Amanda Lund
- Â Roberta Kaplan 2 episodes, 2015-2019
- Ben Folds
- Â Nathan Cherry / ... 2 episodes, 2014-2016
- Questlove
- Â Self / ... 1 episode, 2016-2018
- Zora Bikangaga
- Â Cairo Resident / ... 1 episode, 2018-2019
- John A. Lorenz
- Â Lakota Indian 2 episodes, 2013-2015
- Alexander Arzu
- Â Student / ... 1 episode, 2018
- Matthew Herington
- Â Various / ... 1 episode, 2015-2019
- Lea Mende
- Â Kidnaped Girl / ... 2 episodes, 2015-2018
- Sarah Beguiristain
- Â Grocer / ... 1 episode, 2015
- Artemis Pebdani
- Â Self - Narrator 1 episode, 2013
- Steven Yeun
- Â Daniel Inouye 1 episode, 2014
- Charlie Day
- Â Allan Pinkerton 1 episode, 2014
- Chip Coffey
- Â Medium / ... 1 episode, 2014
- Parker Posey
- Â Mary Phelps Jacob 1 episode, 2015
- Sam Rockwell
- Â Bugsy Siegel 1 episode, 2015
- Giancarlo Esposito
-  Andrés Pico 1 episode, 2015
- Octavia Spencer
- Â Harriet Tubman 1 episode, 2015
- Topher Grace
- Â Milton Bradley 1 episode, 2015
- Ellie Kemper
- Â Nellie Bly 1 episode, 2015
- Blake Anderson
- Â Alexey Leonov 1 episode, 2015
- Liev Schreiber
- Â Victor Lustig 1 episode, 2016
- Lin-Manuel Miranda
- Â Self - Narrator 1 episode, 2016
- Ed Helms
- Â William McMasters 1 episode, 2016
- Gabourey Sidibe
- Â Ella Fitzgerald 1 episode, 2016
- Solomon Georgio
- Â Self - Narrator 1 episode, 2018
- John Early
- Â Self - Narrator 1 episode, 2019
- Jessica McKenna
- Â Self - Narrator 1 episode, 2019
- Derrick Beckles
- Â Self - Narrator 1 episode, 2013
- James Atkinson
- Â Self - Narrator 1 episode, 2013
- BJ Porter
- Â Self - Narrator 1 episode, 2013
- Erin Rohr
- Â Self - Narrator 1 episode, 2013
- James Hong
- Â Hyotaro Inouye 1 episode, 2014
- Retta
- Â Sylvia Robinson 1 episode, 2014
- Mary Elizabeth Ellis
- Â Dorothy Fuldheim 1 episode, 2015
- Ryan Phillippe
- Â Benjamin Hayes 1 episode, 2015
- Christopher Meloni
- Â Othneil Marsh 1 episode, 2015
- Adam Devine
- Â Pavel Belyayev 1 episode, 2015
- Sarah Ramos
- Â Maggie Fox 1 episode, 2016
- Anthony Edwards
- Â Giles Allen 1 episode, 2016
- Dwight Yoakam
- Â Jesse Benton 1 episode, 2016
- Tiffany Haddish
- Â Self - Narrator 1 episode, 2018
- Gabe Liedman
- Â Self - Narrator 1 episode, 2018
- Shaun Diston
- Â Self - Narrator 1 episode, 2018
- Michael Rohr
- Â Self - Narrator 1 episode, 2013
- Nick Kroll
- Â Ronald Reagan 1 episode, 2014
- Brandon T. Jackson
- Â Robert Smalls 1 episode, 2014
- Jerry Minor
- Â Edgar Nixon 1 episode, 2014
- Chelsea Peretti
- Â Ann Druyan 1 episode, 2015
- Sam Richardson
- Â Jim Brown 1 episode, 2015
- Ben Covette
- Â Guy 'Machine Gun' Molony 1 episode, 2015
- Elizabeth Olsen
- Â Norma Kopp 1 episode, 2016
- Rachel Bloom
- Â Self - Narrator 1 episode, 2018
- Ashley Nicole Black
- Â Self - Narrator 1 episode, 2018
- Jane Levy
- Â Self - Narrator 1 episode, 2019
- Betsy Sodaro
- Â Mary Mallon 1 episode, 2019
- Samira Wiley
- Â Bessie Coleman 1 episode, 2019
- Nicole Byer
- Â Self - Narrator 1 episode, 2019
- Ryan Gaul
- Â Self - Narrator 1 episode, 2019
- Jon Lovett
- Â Self - Narrator 1 episode, 2019
- Jason Schwartzman
- Â Ralph Nader 1 episode, 2013
- Bill Hader
- Â John Pemberton 1 episode, 2013
- Alie Ward
- Â Self - Narrator 1 episode, 2013
- Michael Angarano
- Â Walt Disney 1 episode, 2014
- Adrianne Palicki
- Â Kate Warne 1 episode, 2014
- Jordan Peele
- Â Percy Julian 1 episode, 2014
- Eugene Cordero
- Â King Kalani'opu'u 1 episode, 2014
- Terrell Suggs
- Â Self - Football Player 1 episode, 2014
- Brian Mganga
- Â Young Robert Smalls 1 episode, 2014
- Ben Schwartz
- Â Meyer Lansky 1 episode, 2015
- Noah Wyle
- Â Thomas Nast 1 episode, 2015
- Kyle Gass
- Â Fred Eaton 1 episode, 2015
- Rudy Mancuso
- Â Manuel Bonilla 1 episode, 2015
- Emily R. Wilson
- Â Self - Narrator 1 episode, 2015
- Kevin Pollak
- Â Ciro Terranova 1 episode, 2016
- Bokeem Woodbine
- Â George Washington 1 episode, 2016
- Ronda Rousey
- Â Gallus Mag 1 episode, 2016
- Billie Joe Armstrong
- Â Charlie Chaplin 1 episode, 2016
- Kirsten Dunst
- Â Agatha Christie 1 episode, 2018
- Amber Tamblyn
- Â Margaret Sanger 1 episode, 2018
- Tatiana Maslany
- Â Emmeline Pankhurst 1 episode, 2018
- Sophia Bush
- Â Bonnie Raines 1 episode, 2019
- Shiri Appleby
- Â Margaret Howe Lovett 1 episode, 2019
- Adam Campbell
- Â George Soper 1 episode, 2019
- DeRon Horton
- Â Ernest Green 1 episode, 2019
- Mano Agapion
- Â Self - Narrator 1 episode, 2019
- Owen Wilson
- Â John Harvey Kellogg 1 episode, 2013
- Simon Helberg
- Â Frank M. Robinson 1 episode, 2013
- Laura Dern
- Â Nellie Bly 1 episode, 2014
- Lindsay Sloane
- Â Nancy Reagan 1 episode, 2014
- Jeffrey Ross
- Â Francis Scott Key 1 episode, 2014
- Ian Roberts
- Â James Madison 1 episode, 2014
- Nathan Fillion
- Â Wernher Von Braun 1 episode, 2015
- Haley Joel Osment
- Â Kid Blink 1 episode, 2015
- Greg Kinnear
- Â Thaddeus Lowe 1 episode, 2015
- Zach Woods
- Â Lee Duncan 1 episode, 2015
- Laura Steinel
- Â Self - Narrator 1 episode, 2015
- Andrew Rannells
- Â Washington Roebling 1 episode, 2016
- Jessie Ennis
- Â Ella Cherry 1 episode, 2016
- Louie Anderson
- Â Winston Churchill 1 episode, 2016
- Joel McHale
- Â Sheriff George Corwin / ... 1 episode, 2018
- John Michael Higgins
- Â Wilhelm von Osten 1 episode, 2018
- Shannon Woodward
- Â Ida Tarbell 1 episode, 2018
- Raven-Symoné
- Â Nichelle Nichols 1 episode, 2018
- Kyle Bornheimer
- Â Ghost Army Soldier 1 episode, 2018
- Sara Rue
- Â Mary Jane Heaster 1 episode, 2019
- Q'orianka Kilcher
- Â LaNada Means 1 episode, 2019
- Frankie Shaw
- Â Hedy Lamarr 1 episode, 2019
- Rick Overton
- Â Chicago Tribune Editor 1 episode, 2019
- Brian Huskey
- Â Dr. Feelgood / ... 1 episode, 2019
- Luke Wilson
- Â Will Keith Kellogg 1 episode, 2013
- Will Forte
- Â Edwin Booth 1 episode, 2013
- Ike Barinholtz
- Â August Spies 1 episode, 2013
- Andy Daly
- Â Teddy Roosevelt 1 episode, 2013
- Steve Little
- Â Mark Twain 1 episode, 2013
- Jon Daly
- Â Kris Kristofferson 1 episode, 2014
- Jonah Ray
- Â Self - Narrator 1 episode, 2014
- James Adomian
- Â Alexander Cochrane 1 episode, 2014
- Jason Alexander
- Â Boss Tweed 1 episode, 2015
- George Wallace
- Â Bill Russell 1 episode, 2015
- Rowdy
- Â Rin Tin Tin 1 episode, 2015
- Jenna Fischer
- Â Katharine Wright 1 episode, 2016
- Mary Lynn Rajskub
- Â Effie Cherry 1 episode, 2016
- Taylor Schilling
- Â Emily Roebling 1 episode, 2016
- Cole Sand
- Â Archie Roosevelt 1 episode, 2017
- Alexander Skarsgård
- Â Dr. James Dunn 1 episode, 2018
- Jorma Taccone
- Â Memed II 1 episode, 2018
- Keir O'Donnell
- Â Mullen 1 episode, 2018
- Method Man
- Â Joseph Saddler A.K.A. Grandmaster Flash 1 episode, 2018
- Missi Pyle
- Â Christa Gruhle 1 episode, 2019
- Malin Akerman
- Â Beulah Annan 1 episode, 2019
- Cheryl Hines
- Â Lady Bird Johnson 1 episode, 2019
- Dante Basco
- Â The Rabbit 1 episode, 2019
- Kiele Sanchez
- Â Emma Pulaski 1 episode, 2019
- Calvin Dutton
- Â Sam Cooke 1 episode, 2019
- Kumail Nanjiani
- Â Lakota Chief 1 episode, 2013
- Lamorne Morris
- Â Martin Luther King Jr. 1 episode, 2013
- Jonathan Ames
- Â Junius Booth 1 episode, 2013
- Ben Hoffman
- Â Newscaster 1 episode, 2013
- Karey Dornetto
- Â Self - Narrator 1 episode, 2014
- Molly McAleer
- Â Self - Narrator 1 episode, 2014
- Dennis Quaid
- Â Lucky Luciano 1 episode, 2015
- Maya Rudolph
- Â The Black Widow - Griselda Blanco 1 episode, 2015
- Fortune Feimster
- Â Self - Narrator 1 episode, 2015
- Maestro Harrell
- Â Louis Armstrong 1 episode, 2015
- Cameron Esposito
- Â Self - Narrator 1 episode, 2015
- Holly Laurent
- Â Self - Narrator 1 episode, 2015
- John Cho
- Â William Shakespeare 1 episode, 2016
- Alexandra Grey
- Â Marsha P. Johnson 1 episode, 2016
- Noah Ziggy James
- Â Quentin Roosevelt 1 episode, 2017
- David Harbour
- Â Vietnam Memorial Head 1 episode, 2018
- Alex Karpovsky
- Â Zvi Aharoni 1 episode, 2018
- Zach Anner
- Â Man in Wheelchair 1 episode, 2018
- Lake Bell
- Â Belva Gaertner 1 episode, 2019
- Amandla Stenberg
- Â Elizabeth Eckford 1 episode, 2019
- Justice Smith
- Â Ptolemy 1 episode, 2019
- Adam Beach
- Â Richard Oakes 1 episode, 2019
- Paul Rust
- Â John Wojtowicz 1 episode, 2019
- Angela Trimbur
- Â USC Dropout Cult Member 1 episode, 2019
- Jay Duplass
- Â Dr. John C. Lilly 1 episode, 2019
- Kristen Wiig
- Â Patty Hearst 1 episode, 2013
- Adam Scott
- Â John Wilkes Booth 1 episode, 2013
- Alfred Molina
- Â Sir Arthur Conan Doyle 1 episode, 2013
- Matt Jones
- Â Self - Narrator 1 episode, 2014
- Kurt Braunohler
- Â Self - Narrator 1 episode, 2014
- Eric Falconer
- Â Self - Narrator 1 episode, 2014
- Derek Miller
- Â Self - Narrator 1 episode, 2014
- Dave Ross
- Â Self - Narrator 1 episode, 2014
- Mark Proksch
- Â Self - Narrator 1 episode, 2015
- Andre Royo
- Â King Oliver 1 episode, 2015
- Echo Kellum
- Â Lew Alcindor 1 episode, 2015
- Greg Worswick
- Â Self - Narrator 1 episode, 2015
- Andrea Savage
- Â Addie Cherry 1 episode, 2016
- Chris Witaske
- Â Alexander Hamilton 1 episode, 2017
- Angus Sampson
- Â Hughes 1 episode, 2018
- Jillian Bell
- Â Clara McMillen 1 episode, 2018
- Mandy Moore
- Â Clara Barton 1 episode, 2018
- O'Shea Jackson Jr.
- Â Clive Campbell A.K.A. DJ Kool Here 1 episode, 2018
- Kimiko Glenn
- Â Maya Lin 1 episode, 2018
- Sean Berdy
- Â Frank Bowe 1 episode, 2018
- Grant Imahara
- Â Frank Inouye 1 episode, 2018
- Dermot Mulroney
- Â Georges Ladoux 1 episode, 2019
- Camille Chen
- Â Yoko Ono 1 episode, 2019
- Niles Fitch
- Â Michael Patrick 1 episode, 2019
- June Diane Raphael
- Â Isabella Stewart Gardner 1 episode, 2013
- Bradley Whitford
- Â William Jennings Bryan 1 episode, 2013
- Kevin Nealon
- Â The Grand Dragon 1 episode, 2013
- David Cross
- Â Baron von Steuben 1 episode, 2014
- Henry Winkler
- Â Zenas (Rhymes with Penis) Fisk Wilber 1 episode, 2015
- Jessica Meraz
- Â Self - Narrator 1 episode, 2015
- Jane Krakowski
- Â Sheralee 1 episode, 2018
- Casino
- Â Clever Hans 1 episode, 2018
- Ajani A.J. Murray
- Â Support 504 1 episode, 2018
- Dave Foley
- Â Alexis Pulaski 1 episode, 2019
- John Francis Daley
- Â James J. Andrews 1 episode, 2019
- Justin Bartha
- Â Thomas H. Ince 1 episode, 2019
- Gary Anthony Williams
- Â Ted Patrick 1 episode, 2019
- Megan Cavanagh
- Â Penny Marshall 1 episode, 2019
- Dallas Goldtooth
- Â John Trudell 1 episode, 2019
- Olivia Trujillo
- Â Arsinoe 1 episode, 2019
- Will Sasso
- Â Frank Nitti 1 episode, 2013
- Colton Dunn
- Â Self - Narrator 1 episode, 2014
- Morgan Murphy
- Â Self - Narrator 1 episode, 2014
- Paul F. Tompkins
- Â Self - Narrator 1 episode, 2015
- Dan Harmon
- Â Self - Narrator 1 episode, 2015
- Jadon Wells
- Â Young Thaddeus Lowe 1 episode, 2015
- John Levenstein
- Â Self - Narrator 1 episode, 2015
- Abbi Jacobson
- Â Gloria Steinem 1 episode, 2018
- Thomas Mann
- Â Little Baby Hitler 1 episode, 2018
- Lauren Potter
- Â Ventilator Woman 1 episode, 2018
- Elyse Cole
- Â Ann Putnam 1 episode, 2018
- Alison Brie
- Â Thea Spyer 1 episode, 2019
- Zahn McClarnon
- Â Adam Fortunate Eagle 1 episode, 2019
- Lilan Bowden
- Â Elisa Boyer 1 episode, 2019
- Ali Ghandour
- Â Prince Aly Khan 1 episode, 2019
- Moshe Kasher
- Â Albert Parsons 1 episode, 2013
- Henry Phillips
- Â Self - Narrator 1 episode, 2014
- Gloria Calderón Kellett
- Â Self - Narrator 1 episode, 2015
- Ali Stroker
- Â Judy Heumann 1 episode, 2018
- Tessa Thompson
- Â Eartha Kitt 1 episode, 2019
- Erin McGathy
- Â Self - Narrator 1 episode, 2014
- Ashley Barnhill
- Â Self - Narrator 1 episode, 2015
- Devi Ohira
- Â Genghis Khan's Mother 1 episode, 2018
- Connie Britton
- Â Patricia Shaheen 1 episode, 2013
- Fred Willard
- Â Deep Throat 1 episode, 2013
- Erin Henriques
- Â Marion Davies 1 episode, 2019
- Nick Offerman
- Â Johnny Cool 1 episode, 2013
- Ally Johnson
- Â Self 1 episode, 2013
- Zander Ayeroff
- Â LGBT Teen 1 episode, 2016
- Zach Paez
- Â Various 1 episode, 2013
- Adam DeCoster
- Â Self - Foley Artist 1 episode, 2014
- Keli'i
- Â Hawaiian 1 episode, 2014
- Skyler Shelley
- Â LGBT Teen 1 episode, 2016
- Michael Hagiwara
- Â Mr. Emi 1 episode, 2018
- Aidan Potter
- Â Various 1 episode, 2013
- Tom Stone
- Â Self - Legendary Hawaiian Surfer 1 episode, 2014
- Scott Takeda
- Â Frank Inouye 1 episode, 2018
- Raymond Ochoa
- Â Various 1 episode, 2013
- Kristin Pitts
- Â Dancer 1 episode, 2015
- Ricardo Tirado
- Â Various 1 episode, 2013
- Zac Burk
- Â Various 1 episode, 2013
- Dylan Henry Lau
- Â Temujin 1 episode, 2018
- Clint Culp
- Â Policeman 1 episode, 2013
- Beth Cahill
- Â Onlooker 1 episode, 2013
- Corey Weber
- Â Tim- The Cowboy 1 episode, 2013
- Benjamin Poe
- Â Policeman 1 episode, 2013
- Allen Marsh
- Â Various 1 episode, 2013
- Joseph Zinsman
- Â Soldier 1 episode, 2013
- Dakota Black
- Â Lakota Indian 1 episode, 2013
- Paco Romane
- Â Self 1 episode, 2013
- Abdul Abukusumo
- Â South American 1 episode, 2013
- Sabrina Culver
- Â Various 1 episode, 2014
- Antonio Piluso
- Â Bar Patron 1 episode, 2014
- Jamie Love
- Â Senator 1 episode, 2014
- Vincent Marinelli
- Â Radio Producer 1 episode, 2014
- Matt Dority
- Â Doctor 1 episode, 2014
- Jett Dunlap
- Â Various 1 episode, 2014
- David Simon
- Â Self 1 episode, 2015
- Amber Wegner
- Â Meter Maid 1 episode, 2015
- Katie McCabe
- Â 19th Century Woman 1 episode, 2015
- Ronald James Hoff Jr
- Â Pirate 1 episode, 2015
- Al Bowen
- Â Pueblo Indian 1 episode, 2015
- Josh Price
- Â Bully 1 episode, 2015
- Noelle Bonhomme
- Â Edison's Assistant 1 episode, 2015
- Chris Scagos
- Â Conquistador 1 episode, 2015
- Ryan Philbin
- Â Tyler Rose 1 episode, 2015
- Michael Carnegie
- Â Vasily Smyslov 1 episode, 2015
- Cody Buchanan
- Â Native American 1 episode, 2015
- Cameron Obscura
- Â Las Vegan 1 episode, 2015
- Collin Blair
- Â Rusty Staub 1 episode, 2016
- Kyle Merryman
- Â various (Snotty Macready fan) 1 episode, 2016
- Tina Grimm
- Â Playboy Bunny 1 episode, 2018
- Alice Kina Diehl
- Â 504 Protester 1 episode, 2018
- Kc Monnie
- Â Gatsby 1 episode, 2018
- David Radcliff
- Â Disability Rights Activist 1 episode, 2018
- Cheri Adams
- Â Dorothy L. Sayers 1 episode, 2018
- Erik Groysman
- Â Bass Man 1 episode, 2018
- Laurence Guillermo
- Â Tutor / ... 1 episode, 2019
- Bruce M. Stockert
- Â Doctor / ... (uncredited) 14 episodes, 2019
- Kyle David Crosby
- Â Bootlegger / ... (uncredited) 3 episodes, 2013
- Monique Farah
- Â Caesar's girlfriend / ... (uncredited) 2 episodes, 2019
- Mika Shepherd
- Â German Engineering Student / ... (uncredited) 2 episodes, 2019
- George Thomas Mansel
- Â Attorney (uncredited) 1 episode, 2014
- Cici Leah Campbell
- Â Townfolk (uncredited) 1 episode, 2013
- Kaci Beeler
- Â Self - Interviewee (uncredited) 1 episode, 2013
- Frank Mercuri
- Â Kellogg Patient (uncredited) 1 episode, 2013
- Michael Kearney
- Â Interviewee (uncredited) 1 episode, 2013
- Polly W. LePorte
- Â Kellogg Patient (uncredited) 1 episode, 2013
- Lacie Madison
- Â Party Guest (uncredited) 1 episode, 2013
- Laura Hudock
- Â June Carter Cash (uncredited) 1 episode, 2014
- Tara Kuhnert Hotchkis
- Â Journalist (uncredited) 1 episode, 2014
- Brittany Marie Batchelder
- Â young Friend (uncredited) 1 episode, 2014
- Eric Womack
- Â Fire Marshal (uncredited) 1 episode, 2014
- Emily Zemler
- Â Janis Joplin (uncredited) 1 episode, 2014
- Justin Levine
- Â Orson Welles' Assistant (uncredited) 1 episode, 2014
- Tiffany Simone English
- Â Orphan Girl (uncredited) 1 episode, 2014
- Jeffrey James Lippold
- Â NASA Army Captain / ... (uncredited) 1 episode, 2015
- Jennifer Gable
- Â Comedian (uncredited) 1 episode, 2015
- Drew Neal Horton
- Â Ship Member (uncredited) 1 episode, 2015
- John Paul Blanco
- Â Native American (uncredited) 1 episode, 2015
- Chris Jackson
- Â Self (uncredited) 1 episode, 2016
- Stephanie Walters
- Â Various (uncredited) 1 episode, 2016
- LynNita Ellis
- Â Disco Rebel (uncredited) 1 episode, 2016
- Monique Carmona
- Â Sanitarium Nurse (uncredited) 1 episode, 2016
- Russell Nauman
- Â Various (uncredited) 1 episode, 2016
- Allan Graf
- Â Bank President (uncredited) 1 episode, 2018
- Jeff Marc Grossman
- Â Bass Band Drummer (uncredited) 1 episode, 2018
- Erwin Portillo
- Â Jamuhka Soldier (uncredited) 1 episode, 2018
- Eric Rangel
- Â B-Boy (uncredited) 1 episode, 2018
- J.B. Abajian
- Â Disability Rights Activist (uncredited) 1 episode, 2018
- Amanda Cleghorn
- Â Dancer (uncredited) 1 episode, 2019
- Jonesy
- Â Happy Felsch (uncredited) 1 episode, 2019
- Dean Jacobs
- Â Impaled Boyar (uncredited) 1 episode, 2019
- Mike Tsirklin
- Â Rebel Egyptian Soldier (uncredited) 1 episode, 2019
- Tennile Marie Goosic
- Â Elizabeth Frankenstein (uncredited) 1 episode, 2019
- Delia Rawdon
- Â Activist (uncredited) 1 episode, 2019
- Jason Klamm
- Â Robert Williamson (uncredited) 1 episode, 2019
- Michelle Lynn
- Â Thelma Mothershed & Bessie Coleman Fan (uncredited) 1 episode, 2019
- Lanier McKinney
- Â Dancer #3 (uncredited) 1 episode, 2019
