- Robin Williams
- Popeye
- Shelley Duvall
- Olive Oyl
- Ray Walston
- Poopdeck Pappy
- Paul Dooley
- Wimpy
- Paul L. Smith
- Bluto
- Richard Libertini
- Geezil
- Donald Moffat
- The Taxman
- MacIntyre Dixon
- Cole Oyl
- Roberta Maxwell
- Nana Oyl
- Donovan Scott
- Castor Oyl
- Allan F. Nicholls
- Rough House
- Wesley Ivan Hurt
- Swee'pea
- Bill Irwin
- Ham Gravy - The Old Boyfriend
- Robert Fortier
- Bill Barnacle - The Town Drunk
- David McCharen
- Harry Hotcash - The Gambler
- Sharon Kinney
- Cherry - His Moll
- Peter Bray
- Oxblood Oxheart - The Fighter
- Linda Hunt
- Mrs. Oxheart - His Mudder
- Geoff Hoyle
- Scoop - The Reporter
- Wayne Robson
- Chizzelflint - The Pawnbroker
- Larry Pisoni
- Chico - The Dishwasher
- Carlo Pellegrini
- Swifty - The Cook
- Susan Kingsley
- La Verne - The Waitress
- Michael Christensen
- Splatz - The Janitor
- Ray Cooper
- The Preacher
- Noel Parenti
- Slick - The Milkman
- Karen McCormick
- Rosie - The Milkmaid
- John E. Bristol
- Bear - The Hermit
- Julie Janney
- Mena Walfleur - A Steinette
- Patty Katz
- Mina Walfleur - A Steinette
- Diane Shaffer
- Mona Walfleur - A Steinette
- Nathalie Blossom
- Blossom Walfleur - A Steinette
- Dennis Franz
- Spike - A Tough
- Alan Autry
- Slug - A Tough
- Ned Dowd
- Butch - A Tough
- Hovey Burgess
- Mort - A Tough
- Roberto Messina
- Gozo - A Tough
- Pietro Torrisi
- Bolo - A Tough
- Margery Bond
- Daisy - A Housewife
- Judy Burgess
- Petunia - A Housewife
- Saundra MacDonald
- Violet - A Housewife
- Eve Knoller
- Min - A Housewife
- Peggy Pisoni
- Pickelina - A Housewife
- Barbara Zegler
- Daphne - A Housewife
- Paul Zegler
- Mayor Stonefeller - The Official
- Pamela Burrell
- Mrs. Stonefeller
- David Arkin
- The Mailman / Policeman
- Klaus Voormann
- Von Schnitzel - The Conductor
- Doug Dillard
- Clem - The Banjo Player
- Van Dyke Parks
- Hoagy - The Piano Player
- Stan Wilson
- Oscar - The Barber
- Roberto Dell'Acqua
- The Chimneysweep
- Valerie Velardi
- Cindy - The Drudge
- Jack Mercer
- Popeye - Animated Prologue
