- Claire Trevor
- Dallas
- John Wayne
- Ringo Kid
- Andy Devine
- Buck
- John Carradine
- Hatfield
- Thomas Mitchell
- Doc Josiah Boone
- Louise Platt
- Mrs. Lucy Mallory
- George Bancroft
- Marshal Curley Wilcox
- Donald Meek
- Samuel Peacock
- Berton Churchill
- Ellsworth Henry Gatewood
- Tim Holt
- Lt. Blanchard
- Tom Tyler
- Luke Plummer
- Dorothy Appleby
- Girl in Saloon
- Frank Baker
- (uncredited)
- Chief John Big Tree
- Indian Scout
- Ted Billings
- Bit Part
- Wiggie Blowne
- Bit Part
- Danny Borzage
- (uncredited)
- Ed Brady
- Lordsburg Saloon Owner
- Fritzi Brunette
- Bit Part
- Yakima Canutt
- Cavalry Scout / Indian Attacking Stagecoach (uncredited)
- Nora Cecil
- Boone's Landlady
- Steve Clemente
- Bit
- Bill Cody
- Rancher
- Jack Curtis
- Bartender
- Marga Ann Deighton
- Mrs. Pickett
- Patricia Doyle
- Bit Part
- Tex Driscoll
- Bit Part
- Johnny Eckert
- Small Role
- Franklyn Farnum
- Deputy Frank
- Francis Ford
- Sgt. Billy Pickett
- Brenda Fowler
- Mrs. Gatewood
- Olin Francis
- Lordsburg Townsman
- Helen Gibson
- Girl in Saloon
- Don Hawks
- Small Role
- Robert Homans
- Ed - Editor
- William Hopper
- Sergeant
- George Huggins
- Barfly
- Si Jenks
- Bartender
- Cornelius Keefe
- Capt. Whitney
- Florence Lake
- Mrs. Nancy Whitney
- Al Lee
- Small Role
- Duke R. Lee
- Lordsburg Sheriff
- Theodore Lorch
- Lordsburg Express Agent
- Chris-Pin Martin
- Chris
- Jim Mason
- Jim - Tonto Express Agent
- Louis Mason
- Tonto Sheriff
- Merrill McCormick
- Ogler
- J.P. McGowan
- (uncredited)
- Walter McGrail
- Capt. Sickel
- Paul McVey
- Pony Express Agent
- Jack Mohr
- Small Role
- Kent Odell
- Billy Pickett Jr
- Artie Ortego
- Lordsburg Bar Patron
- Vester Pegg
- Hank Plummer
- Jack Pennick
- Jerry - Tonto Bartender
- Chris Phillips
- Small Role
- Joe Rickson
- Ike Plummer
- Buddy Roosevelt
- Rancher
- Elvira RÃos
- Yakima
- Mickey Simpson
- (uncredited)
- Margaret Smith
- Small Role
- Chuck Stubbs
- (uncredited)
- Harry Tenbrook
- Telegraph Operator
- Leonard Trainor
- Townsman
- Dorothy Vernon
- Townswoman
- Mary Kathleen Walker
- Lucy's Infant
- Blackjack Ward
- Townsman
- Bryant Washburn
- Capt. Simmons
- Whitehorse
- Indian Chief
- Hank Worden
- Cavalryman
