- Key Dieck
- Deadpool / Wade Wilson
- Renelle Palmer
- Black Widow / Natalia 'Natasha' Romanova
- Megan Harley
- Catwoman / Selena Kyle
- Kain Malice
- Reaper
- Nick Drye
- Wraith
- Josh Phillips
- Norman Osborn
- Melissa Varnum
- Kitrina Falcone
- Kayla Farris
- Barbara Gordon
- Tommy Evans
- Wolverine
- Elizabeth Schwartze
- Agent Maria Hill
- Sylvester Clayton
- Reaper's Thug
- Zeb Strickland
- Reaper's Thug
- Mike Moorman
- Reaper's Thug
- Josh Murphy
- Reaper's Thug
- Christopher Seward
- Reaper's Thug
- Tanner Evans
- Reaper's Thug
- David Leslie
- Reaper's Thug
- Jason Carpenter
- Reaper's Thug
- Tyler Shelby
- Reaper's Thug
- Ricky Anderson Jr.
- Reaper's Thug
- Tim Petrick
- Reaper's Thug
- David Knight III
- Reaper's Thug
- Derek Shetrone
- Reaper's Thug
- Gary Palmer
- Reaper's Thug
- Todd Brannon
- Grizzly Adams
- Gerald Holcomb
- Head Bitch Thug
- Steven Sabell
- 'Ricky' Thug
- Zach Ledeboer
- Loud Mouth Thug
- Brad Brown
- Homeless Onlooker
- Bryan McCracken
- Unlucky Punk That Deadpool Killed #1
- Jordan Robinson
- Unlucky Punk That Reaper Killed #1
- Ben Johnson
- Two-Face / Man in the Darkness
- Adriana Adams
- (uncredited)
- Randy Duffey
- (uncredited)
