- Paul Newman
- Henry Gondorff
- Robert Redford
- Johnny Hooker
- Robert Shaw
- Doyle Lonnegan
- Charles Durning
- Lt. Wm. Snyder
- Ray Walston
- J.J. Singleton
- Eileen Brennan
- Billie
- Harold Gould
- Kid Twist
- John Heffernan
- Eddie Niles
- Dana Elcar
- F.B.I. Agent Polk
- Jack Kehoe
- Erie Kid
- Dimitra Arliss
- Loretta
- Robert Earl Jones
- Luther Coleman
- James Sloyan
- Mottola
- Charles Dierkop
- Floyd (Bodyguard)
- Lee Paul
- Bodyguard
- Sally Kirkland
- Crystal
- Avon Long
- Benny Garfield
- Arch Johnson
- Combs
- Ed Bakey
- Granger
- Brad Sullivan
- Cole
- John Quade
- Riley
- Larry D. Mann
- Train Conductor
- Leonard Barr
- Burlesque House Comedian
- Paulene Myers
- Alva Coleman
- Joe Tornatore
- Black Gloved Gunman
- Jack Collins
- Duke Boudreau
- Tom Spratley
- Curly Jackson
- Kenneth O'Brien
- Greer
- Ken Sansom
- Western Union Executive
- Ta-Tanisha
- Louise Coleman
- William 'Billy' Benedict
- Roulette Dealer
- Jack Berle
- Gambler
- Nick Borgani
- Tailor
- Patricia Bratcher
- Manicurist
- Robert Brubaker
- Bill Clayton from Pittsburgh
- Robert Buckingham
- Gambler
- Peter Eastman
- Poker Player
- Richard Elmore
- Gambler
- Bob Folkerson
- Gambler
- Kathleen Freeman
- Kid Twist's Wife
- Susan French
- Landlady
- Sig Frohlich
- Gambler
- Ralph Gambina
- Gambler
- Clarke Gordon
- Mr. Lombard
- Frank Green
- Gambler
- Jack Griffin
- Cabbie
- Bob Harks
- Pedestrian
- George Holmes
- Gambler
- Sid Kane
- Cashier #2
- Bruce Kimball
- Lacey the Bouncer
- Mike Lally
- Gambler
- Alexander Lockwood
- Landlord
- Tom McDonough
- Gambler
- Jim Michael
- Bartender
- Chuck Morrell
- F.B.I. Agent Chuck
- Byron Morrow
- Mr. Jameson from Chicago
- Richard Niehaus
- Train Passenger
- Jessica Rains
- Secretary
- Al Roberts
- Gambler
- Edwin Rochelle
- Gambler
- Clark Ross
- Man at Bar
- Pearl Shear
- Lady in Phone Booth
- Arthur Tovey
- Bank Officer
- Guy Way
- Gambling Den Boss
