- Steve-O
- Self / Satan / Stingray / Steve-O Doll
- Preston Lacy
- Big Fat Party Guy / XXXL / Before / Michael Moore / Preston Lacy Doll / Ogre / Mrs. Smith
- Jason 'Wee Man' Acuña
- My Little Buddy / Wee-Man Doll / Cricket / Mobutu
- Chris Pontius
- Jesus
- Clifton Collins Jr.
- Tijuana Cop #1 / Minion / Miranda
- Jacob Vargas
- Tijuana Cop #2 / Announcer / Charlotte
- Dian Bachar
- Gregg / Luigi / Cathy Ave / Joshua Benson / Other Fly / Stranger
- Lee Majors
- Dr. Lakin / Announcer / Lieutenant / Six Million Year-Old Man / Cowboy
- Sam Macaroni
- Chad / Kid / Dick Weston Fernandez / Jeffry Sutton / Dealer / T-Rex (as a different name)
- Jason Mewes
- Carrie
- Judd Nelson
- Fear Factor Host / Judd
- Danny Trejo
- Crow
- Dimitry Elyashkevich
- Ace Glover / Jackoff Smirnoff
- Tony Cox
- Stubbs
- J.J. Darshaw
- Gringo
- Jessica Diz
- Hot Drunken Latina
- Sevier Crespo
- Drug Dealer / Fear Factor Contestant #2
- Gustavo Alvarez
- Mario / Leche
- Mike McGuiness
- Fear Factor Contestant #1
- Jason Fijal
- Manny
- Jon Greenhalgh
- Moe
- Mick Page
- Jack
- Richard Portnow
- Sergeant
- Ahmet Zappa
- Army Host
- Pete Yorn
- Bobby Peacock
- Michael O'Hearn
- MP Johnson / Dubois
- Steve Schleinitz
- MP Jackson / Coover
- Estefania Iglesias
- Satan's Hottie / Lakin Girl #2 (as Iglesias Estefania)
- Ryan Simonetti
- Self
- Dave Buckner
- Self
- Lamont Johnson
- Gizzards
- Benny Wasserman
- Einstein
- Tammy Vallejos
- Bridgitte
- Tara Jane
- Lakin Girl #1
- Mayte Garcia
- Lakin Girl #3 / Cantalope
- Nicole Marie Lenz
- Lakin Girl #4
- Cheo Solder
- Beef Ramington
- Jason Dean Booher
- After
- Tabitha Taylor
- Hot Blonde
- Jamie Hagen
- Hot Brunette
- Camille Langfield
- Red Headed Looney
- Brandon Ellis
- Announcer
- Elizabeth Fisher
- Girl
- Terry Rhoads
- Doctor / Interventionist
- Christina Pazsitzky
- Lexus from Texas / Girl Fly
- Salim Grant
- Filthy Strip Club Announcer
- Miguel A. Núñez Jr.
- Jimmy Winks / MBA Dude / Races Host
- Vincent Laresca
- Drug-Lord Jose Carlos
- Chris Jones
- Bodyguard #1
- Raúl Conde
- Bodyguard #2
- Rick Najera
- Alfredo Garcia Steven / Rick
- Abraham Benrubi
- Max Gottlieb
- Elisa Donovan
- Suzy Gottlieb
- Marcy Goldman
- Eythel
- Jonah Rooney
- Bully
- Ian Somerhalder
- Guy
- Ehren McGhehey
- Jimmy Gonzalas
- Eugenio Derbez
- Derbez, Eugenio
- Jessica Albertson
- Self - Nurse #1
- Verina Marcel
- Nurse #2
- Art Chudabala
- Samantha
- Lobo Sebastian
- Chango
- Gary Gubrrier
- Black Bitch
- Manny Puig
- Manny the Gator Guy
- Patrick O'Hagan
- Teacher
- Mackenzie King
- Girl
- Keren Gilbert
- Cowgirl
- Adam Vetri
- Mr. Smith
- Don Abbatiello
- Boat Thug
- Karla Cavalli
- Waitress
- Faith Majors
- Ms. Jones
- Pancho Moler
- Minja
- Tim Montijo
- Soldier
- Scott Norris
- Prison inmate
- Alveraz Ricardez
- Drug dealer
- Danielle Sapia
- Anna
- Jasmine Waltz
- Bunny
