- Chevy Chase
- Clark Griswold
- Beverly D'Angelo
- Ellen Griswold
- Imogene Coca
- Aunt Edna
- Randy Quaid
- Cousin Eddie
- Anthony Michael Hall
- Rusty Griswold
- Dana Barron
- Audrey Griswold
- Eddie Bracken
- Roy Walley
- Brian Doyle-Murray
- Kamp Komfort Clerk
- Miriam Flynn
- Cousin Catherine
- James Keach
- Motorcycle Cop
- Eugene Levy
- Car Salesman
- Frank McRae
- Grover
- John Candy
- Lasky - Guard at Walleyworld
- Christie Brinkley
- The Girl in the Ferrari
- Jane Krakowski
- Cousin Vicki
- John P. Navin Jr.
- Cousin Dale
- Nathan Cook
- Man Giving Directions
- Christopher Jackson
- Pimp
- Mickey Jones
- Mechanic
- John Diehl
- Assistant Mechanic
- Jeannie Dimter Barton
- Dodge City Cashier
- Randy Lowell
- Wyatt Earp
- Virgil Wyaco II
- Indian
- Gerry Black
- Davenport
- James Staley
- Motel Desk Clerk
- Adelaide Wilder
- Car Hop
- Tessa Richarde
- Motel Guest
- Fritz Ford
- Neighbor
- Eric Stacey
- Neighbor
- Scott Perry
- Swat Leader
- Dennis Freeman
- Policeman
- Michael Talbott
- Cowboy
- John Craigmile
- Camel Rider
- Popeye the Dog
- Dinky
- Henry Gibson
- Hotel Clerk
- Frank Pettinger
- Police Officer
- Don Pulford
- Pedestrian With Grocery Bags
- Harold Ramis
- Car Salesman
- Violet Ramis
- Daisy Mabel
- Lorenzo Salviati
- Bar Piano Player
