- Kelly Overton
- Â Vanessa Van Helsing / ... 54 episodes, 2016-2021
- Jonathan Scarfe
- Â Axel Miller 48 episodes, 2016-2021
- Aleks Paunovic
- Â Julius 35 episodes, 2016-2021
- Rukiya Bernard
- Â Doc 28 episodes, 2016-2021
- Vincent Gale
- Â Flesh 28 episodes, 2016-2019
- Christopher Heyerdahl
- Â Sam 27 episodes, 2016-2021
- Jennifer Cheon Garcia
- Â Ivory 24 episodes, 2017-2021
- Jesse Stanley
- Â Oracle / ... 24 episodes, 2018-2021
- Trezzo Mahoro
- Â Mohamad 23 episodes, 2016-2021
- Rowland Pidlubny
- Â Scab / ... 22 episodes, 2016-2019
- Keeya King
- Â Violet 19 episodes, 2019-2021
- Nicole Muñoz
- Â Jack 18 episodes, 2019-2021
- Paul Johansson
- Â Dmitri 16 episodes, 2016-2018
- Hilary Jardine
- Â Susan 14 episodes, 2016-2021
- Missy Peregrym
- Â Scarlett Harker 14 episodes, 2017-2021
- Caroline Cave
- Â Jolene 12 episodes, 2017-2021
- Keith Arbuthnot
- Â Elder / ... 11 episodes, 2016-2018
- Laura Mennell
- Â Rebecca 10 episodes, 2016-2021
- Hannah Cheramy
- Â Dylan 10 episodes, 2016-2021
- Macie Juiles
- Â Callie 10 episodes, 2016-2021
- David Cubitt
- Â John 10 episodes, 2016-2018
- Neal McDonough
- Â Hansen / ... 9 episodes, 2018-2021
- Tricia Helfer
- Â Dracula 9 episodes, 2019-2021
- Duncan Ollerenshaw
- Â Dr. Sholomenko 9 episodes, 2016-2017
- Anna Galvin
- Â Avery 8 episodes, 2019-2021
- Naika Toussaint
- Â Sheema 8 episodes, 2016-2017
- Heather Doerksen
- Â Michaela 7 episodes, 2019-2021
- Andrea Ware
- Â Lucky 7 episodes, 2017
- John DeSantis
- Â Gustov / ... 7 episodes, 2016-2017
- Alison Wandzura
- Â Nicole 6 episodes, 2016
- Donny Lucas
- Â Chad / ... 6 episodes, 2017-2019
- Christina Jastrzembska
- Â Mama 6 episodes, 2016-2021
- John Reardon
- Â Dr. Harrison 5 episodes, 2017-2018
- Terry Chen
- Â Brendan 5 episodes, 2016
- Bzhaun Rhoden
- Â Felix 5 episodes, 2017-2018
- Phil Burke
- Â Mike 4 episodes, 2017-2018
- Peter Bryant
- Â Vice President Eli Newton 4 episodes, 2021
- Julie Lynn Mortensen
- Â Lillian Van Helsing 4 episodes, 2018-2019
- Cassidy Nugent
- Â Tabby 4 episodes, 2018-2019
- Danny Wattley
- Â Dre 4 episodes, 2018
- Ryan Jinn
- Â Lee 4 episodes, 2019
- Michael Jonsson
- Â Barry 4 episodes, 2018
- Teach Grant
- Â Scarhead 4 episodes, 2017-2018
- Ryan Robbins
- Â Taka 4 episodes, 2016-2017
- Raresh DiMofte
- Â Captain Rasto / ... 4 episodes, 2017-2021
- Gia Crovatin
- Â Anastasia / ... 4 episodes, 2016-2017
- Vanessa Walsh
- Â Marybeth 4 episodes, 2018
- Dakota Daulby
- Â Willem 4 episodes, 2019
- Jennifer Spence
- Â B'ah / ... 4 episodes, 2016-2018
- Sarah Desjardins
- Â Catherine 4 episodes, 2016
- Colleen Winton
- Â Abigail 4 episodes, 2017-2019
- Rob 'Sluggo' Boyce
- Â Balthazar 4 episodes, 2016-2021
- Donald Sales
- Â Jeremy / ... 4 episodes, 2018-2021
- Alexa Grace Arlitt
- Â Young Vanessa 4 episodes, 2017-2021
- Luvia Petersen
- Â Sgt. Weathers 4 episodes, 2021
- Matt Phillips
- Â Julius' Feral Dog / ... 4 episodes, 2016-2017
- Camille Marty
- Â Young Scarlett 3 episodes, 2017-2018
- Jason William Day
- Â Refugee / ... 3 episodes, 2016
- Dan Cade
- Â Roberto 3 episodes, 2021
- Kim Coates
- Â Count Dalibor 3 episodes, 2021
- Ali Liebert
- Â Nina 3 episodes, 2021
- Michael Eklund
- Â Abraham Van Helsing / ... 3 episodes, 2018-2019
- Richard Harmon
- Â Max Borman 3 episodes, 2019
- Stephen Lobo
- Â President Davis Park 3 episodes, 2021
- Aaron Douglas
- Â Colonel Nicholson 3 episodes, 2019
- Matus Kvietik
- Â Florian 3 episodes, 2021
- Sarah Arató
- Â Alexandra 3 episodes, 2021
- Tim Perez
- Â Biggs 3 episodes, 2021
- Shane Symons
- Â Ethan Johnson / ... 3 episodes, 2017-2018
- Avery Konrad
- Â Cynthia 3 episodes, 2016
- Jill Teed
- Â President Archer 3 episodes, 2019-2021
- Juraj Rasla
- Â Mehai 3 episodes, 2021
- Holly Elissa
- Â Jennifer 3 episodes, 2019
- Aidan Kahn
- Â Jared 3 episodes, 2016-2018
- Briana Skye
- Â Mira 3 episodes, 2019-2021
- Chris Ippolito
- Â Gorman / ... 3 episodes, 2016-2019
- Alexander Brophy
- Â Owen 3 episodes, 2019
- Kendall Cross
- Â Frankie 3 episodes, 2018
- Michael Kopsa
- Â Raul 3 episodes, 2017
- Joshua Hinkson
- Â Sid 3 episodes, 2019-2021
- Gwynyth Walsh
- Â Magdalene 3 episodes, 2016
- Jennifer Copping
- Â Quaid 3 episodes, 2016
- Olivia Ryan Stern
- Â Chloe 3 episodes, 2017
- Andee Frizzell
- Â The Boss / ... 3 episodes, 2017-2018
- Christopher Rosamond
- Â Charles Harker 3 episodes, 2017-2018
- Christopher Russell
- Â Theo 3 episodes, 2016-2018
- George Klimovich
- Â Young Sam / ... 2 episodes, 2017-2018
- Jessie Fraser
- Â Jessie / ... 2 episodes, 2017-2018
- Tommy Europe
- Â Refugee / ... 2 episodes, 2016
- Adrian Hough
- Â Edward Hawkins 2 episodes, 2018
- Tim Guinee
- Â Ted 2 episodes, 2016
- Em Haine
- Â Cara 2 episodes, 2017-2018
- Glenn Ennis
- Â Lester 2 episodes, 2018
- Elliott Montello
- Â Man 2 episodes, 2018
- Trevor Carroll
- Â Trafficker 2 episodes, 2019
- Reese Alexander
- Â General Lannister 2 episodes, 2021
- Viktória Valúchová
- Â Sorina 2 episodes, 2021
- Tammy Gillis
- Â Monica 2 episodes, 2019
- Christie Burke
- Â Emma 2 episodes, 2016
- Paul Duchart
- Â Pastor 2 episodes, 2017-2018
- John Cassini
- Â Maddox 2 episodes, 2018-2019
- Maddie Phillips
- Â Kit 2 episodes, 2018
- Peter Kelamis
- Â Pauly 2 episodes, 2021
- Cory Gruter-Andrew
- Â Troy Johnson 2 episodes, 2017
- Tom McBeath
- Â Sheriff Walt Turner 2 episodes, 2017
- Nels Lennarson
- Â Deputy Danny Douglas 2 episodes, 2017
- Christina Lewall
- Â Claire / ... 2 episodes, 2018-2021
- Andrea Blesáková
- Â Sister 2 episodes, 2021
- Chad Riley
- Â Vampire Bob 2 episodes, 2016
- Edie Hennessey
- Â Little Girl 2 episodes, 2017
- Tina Georgieva
- Â Teenage Scarlett 2 episodes, 2017
- William Belleau
- Â McGrath 2 episodes, 2017-2018
- Melanie Chan
- Â Survivor 2 episodes, 2019
- Kheon Clarke
- Â Special Op #1 / ... 2 episodes, 2019
- Darren Mann
- Â Ryan 2 episodes, 2017
- Blair Penner
- Â Private Patterson 2 episodes, 2018
- Toby Levins
- Â Bosworth 2 episodes, 2018-2019
- Amanda May
- Â Dark Figure 2 episodes, 2018
- Karina Frislev
- Â Sister / ... 2 episodes, 2019
- Dawn Chubai
- Â TV Broadcaster / ... 2 episodes, 2016
- Enid-Raye Adams
- Â Caitlyn Bruce 2 episodes, 2018
- Kelly Konno
- Â Medical Supervisor 2 episodes, 2018
- Ben Cotton
- Â Campbell 2 episodes, 2016
- Nelson Wong
- Â Nguyen 2 episodes, 2018-2019
- Sandy Robson
- Â Daniel 2 episodes, 2017-2021
- Katerina Katelieva
- Â Sister / ... 2 episodes, 2018
- Jillian Fargey
- Â Ella Harker 2 episodes, 2017-2018
- Michael Patrick Denis
- Â Ted Seward 2 episodes, 2018-2021
- Patricia Cullen
- Â Valerie Seward 2 episodes, 2018-2021
- Maya Chang
- Â Eden Hunter / ... 2 episodes, 2016-2018
- David Allan Pearson
- Â Old Man 1 episode, 2018
- Melissa M. Montgomery
- Â Severe Nurse 1 episode, 2018
- Shawn Macdonald
- Â Clerk 1 episode, 2018
- Crystal Mudry
- Â Wiry Girl 1 episode, 2018
- Camille Mitchell
- Â Mrs. Fontleroy 1 episode, 2018
- Lee Shorten
- Â Master Tsui 1 episode, 2018
- Siobhan Williams
- Â Siobhan 1 episode, 2018
- Sara Canning
- Â Carter / ... 1 episode, 2018
- Jeffrey Ballard
- Â Aaron / ... 1 episode, 2021
- Dario Giordani
- Â Martin 1 episode, 2017
- Steve Bacic
- Â Emmett's Dad 1 episode, 2021
- Jen Araki-Playfair
- Â Young Abby Van Helsing 1 episode, 2021
- Kat Ruston
- Â Zuma 1 episode, 2021
- Tom Cavanagh
- Â Micah 1 episode, 2016
- Jeff Kober
- Â Simon 1 episode, 2018
- Jess McLeod
- Â Shelley 1 episode, 2019
- Paul Wight
- Â Carnage 1 episode, 2019
- Darcy Laurie
- Â Hopper 1 episode, 2021
- Arpad Balogh
- Â Delta #1 1 episode, 2021
- Kyle Strauts
- Â Dominik 1 episode, 2021
- Avionne Dean
- Â Child / ... 1 episode, 2021
- Leonard Tenisci
- Â Oldest Man 1 episode, 2017
- Brent Stait
- Â Dr. Karloff 1 episode, 2018
- Brendan Riggs
- Â Heaton 1 episode, 2018
- Gary Peterman
- Â Abernathy 1 episode, 2018
- Bradley Stryker
- Â Matty 1 episode, 2019
- Natalie Sharp
- Â Shona 1 episode, 2019
- Adam Greydon Reid
- Â Darius 1 episode, 2019
- Ron Selmour
- Â Lukas 1 episode, 2021
- Bert Mitchell
- Â Thinnest Weak Man 1 episode, 2017
- Jill Morrison
- Â Shelley 1 episode, 2018
- Fred Keating
- Â Lorne 1 episode, 2018
- Johnson Phan
- Â Yang Shih 1 episode, 2018
- Zenia Marshall
- Â Kim 1 episode, 2019
- Michael McIntyre
- Â Caged Man 1 episode, 2019
- Rami Kahlon
- Â Shivani 1 episode, 2021
- Catherine Lough Haggquist
- Â Beth 1 episode, 2016
- Jeff Gonek
- Â Weak Man 1 episode, 2017
- C. Ernst Harth
- Â Heavy Set Guard 1 episode, 2018
- Lincoln McGowan
- Â Nelson 1 episode, 2018
- Brodie Marples
- Â Day Walker 1 episode, 2018
- Matreya Scarrwener
- Â Brittney 1 episode, 2019
- Michael Benyaer
- Â Stefan 1 episode, 2021
- Jorge Montesi
- Â Pastor Diaz 1 episode, 2021
- Darren Moore
- Â Vampire 'Raw Steak' 1 episode, 2017
- Ruslan Klimovich
- Â Half Eaten Boy 1 episode, 2017
- Chelsey Reist
- Â Kelly 1 episode, 2018
- Daniel Joseph Rizzuto
- Â Guard #1 1 episode, 2018
- Don Lew
- Â Servant 1 episode, 2018
- Brianna Deutsch
- Â Young Abby 1 episode, 2018
- Richard Meen
- Â Frederick 1 episode, 2021
- Pippa Mackie
- Â Peggy 1 episode, 2016
- Ivan Pecuh
- Â Teenage Boy 1 episode, 2016
- Erin Boyes
- Â Holly 1 episode, 2017
- Michael Adamthwaite
- Â Denis 1 episode, 2017
- Julie Fairweather
- Â Unseen Woman 1 episode, 2017
- Phil Addington
- Â Playground Man #2 1 episode, 2017
- Christiaan Westerveld
- Â Psychic Vampire 1 episode, 2018
- Albert Nicholas
- Â Guard #5 1 episode, 2018
- Irma Leong
- Â Sandra 1 episode, 2018
- Mira Eden
- Â Younger Abby 1 episode, 2018
- Miranda Edwards
- Â Coach 1 episode, 2019
- Khamisa Wilsher
- Â Lucretia 1 episode, 2021
- Marci T. House
- Â Major Stoker 1 episode, 2016
- Lisa Marie DiGiacinto
- Â Jennifer 1 episode, 2016
- Paul Moniz de Sa
- Â Wayne 1 episode, 2017
- Ross Birmann
- Â Playground Man #3 1 episode, 2017
- Marshall Bingham
- Â Hugo 1 episode, 2018
- Jeff Gulka
- Â Diminutive Man 1 episode, 2019
- Rhonda Dent
- Â Charlotte 1 episode, 2019
- Adrian Petriw
- Â Colin / ... 1 episode, 2019
- Tony Alcantar
- Â Officer Rudolph 1 episode, 2019
- Nelson Leis
- Â Leonard 1 episode, 2021
- Alexandra Lukácová
- Â Tattiana 1 episode, 2021
- Andre Tricoteux
- Â Blood Farm Butcher 1 episode, 2016
- William 'Big Sleeps' Stewart
- Â Xavier 1 episode, 2016
- Darren E. Scott
- Â Smith 1 episode, 2016
- Sydney Bell
- Â Mother 1 episode, 2016
- Keith Hearty
- Â Playground Man #4 1 episode, 2017
- Rocky Anderson
- Â Del 1 episode, 2018
- Kiana Rose Fisher
- Â Polly 1 episode, 2018
- Tanya Champoux
- Â Woman 1 episode, 2019
- Jason Griffith
- Â Guard 1 episode, 2019
- Troy Skog
- Â Pharmacist 1 episode, 2019
- Ben Shores
- Â Eye-Patch 1 episode, 2019
- Aqua Asare
- Â Young Woman #1 1 episode, 2019
- Jeff C.
- Â Aaron / ... 1 episode, 2021
- Rob Hayter
- Â Kowalski 1 episode, 2016
- Cody Davis
- Â Nathan 1 episode, 2016
- Dylan Archambault
- Â Junky #1 1 episode, 2016
- Alethea Sholomenko
- Â Cole 1 episode, 2016
- Paula Shaw
- Â Mother Agatha 1 episode, 2017
- John Shaw
- Â Border Officer 1 episode, 2018
- Joel McNichol
- Â Priest 1 episode, 2018
- Sam Dyck
- Â Young Axel 1 episode, 2018
- Adam Murciano
- Â Chained Vampire 1 episode, 2019
- Anett Paulik
- Â Young Woman #2 1 episode, 2019
- Brian Host
- Â Daywalker / ... 1 episode, 2019
- Justin Elliott Ramsey
- Â Unknown Vampire 1 episode, 2021
- James Neate
- Â Junky 1 episode, 2016
- Michael Meneer
- Â Reporter David 1 episode, 2016
- Parker Brando
- Â Collaborator 1 episode, 2016
- Logan Hosie
- Â Vampire Child #1 1 episode, 2016
- Grayson Maxwell Gurnsey
- Â Davey 1 episode, 2017
- Ona Grauer
- Â Vampire Queen Maya 1 episode, 2017
- Leo Rano
- Â Resistance Fighter 1 episode, 2017
- Kwesi Ameyaw
- Â Officer Matthew 1 episode, 2018
- Alex Rose
- Â Marquis de Sade 1 episode, 2018
- Sean Millington
- Â Large Man 1 episode, 2019
- Kareem Malcolm
- Â Medic 1 episode, 2019
- Mark Sweatman
- Â Combatant 1 episode, 2019
- Demord Dann
- Â Special Op #2 1 episode, 2019
- Jimmy Paul
- Â Karaoke Singer Neil 1 episode, 2019
- Ron Wear
- Â DC Cop 1 episode, 2021
- Fiona Vroom
- Â Wendy 1 episode, 2016
- Barbara Wallace
- Â Old Woman 1 episode, 2016
- Kimora Vizzari
- Â Vampire Child #2 1 episode, 2016
- Daniel Cudmore
- Â Skinner #2 1 episode, 2017
- Benjamin Wilkinson
- Â Boss 1 episode, 2017
- Garfield Wilson
- Â Resistance Fighter 1 episode, 2017
- Yvette Dudley-Neuman
- Â Big Mama 1 episode, 2017
- Andy Thompson
- Â Count Laughula 1 episode, 2018
- Sergio Osuna
- Â Private Mendoza 1 episode, 2018
- Paul Dzenkiw
- Â Morgue Tech 1 episode, 2018
- Dave Collette
- Â Buzz 1 episode, 2018
- Raven Sto
- Â Old Woan 1 episode, 2018
- Kasimir MacDougall
- Â Gus 1 episode, 2018
- Klarc Jerome Wilson
- Â Special Op #3 1 episode, 2019
- Bola Omodara
- Â Agent #1 1 episode, 2019
- Erica Govier
- Â Aide 1 episode, 2019
- Mat Lo
- Â Attractive Man 1 episode, 2016
- Mila Tasse
- Â Vampire Child #3 1 episode, 2016
- Billy Wickman
- Â Deputy #1 1 episode, 2017
- Lars Grant
- Â Resistance Fighter 1 episode, 2017
- Anthony Bailey
- Â Skinner #3 1 episode, 2017
- Isaiah Lehtinen
- Â Keith 1 episode, 2018
- Ryan Rosery
- Â Private Raskin 1 episode, 2018
- Aaron Joseph
- Â Security Official 1 episode, 2018
- Haroon Khan
- Â Heckler 1 episode, 2018
- Marc Anthony Williams
- Â Security Official 1 episode, 2019
- Christian Convery
- Â Vampire Child #4A 1 episode, 2016
- Nathan Witte
- Â Cop 1 episode, 2016
- Duke Stevenson
- Â Cop in Cruiser 1 episode, 2016
- Jeremy Jones
- Â Deputy #2 1 episode, 2017
- Byron Brisco
- Â Resistance Fighter 1 episode, 2017
- Christopher Gerard
- Â Blak Tek Guard 1 episode, 2018
- V.G. Winter
- Â Administrator 1 episode, 2018
- Alexandra Staseson
- Â Woman Singer 1 episode, 2018
- Michael Ferreira
- Â Monk 1 episode, 2018
- Shawn Stewart
- Â Loveland Guard 1 episode, 2019
- Mike Kovac
- Â Julius Vampire #1 1 episode, 2016
- Jane Hancock
- Â EMT #1 1 episode, 2016
- Roco Notroff
- Â Vampire Child #4B 1 episode, 2016
- George Stevenson
- Â Vampire Cop in Cruiser 1 episode, 2016
- Panou
- Â Luke 1 episode, 2017
- Braden Haggerty
- Â Resistance Fighter 1 episode, 2017
- Shadow the Dog
- Â Ice 1 episode, 2017
- Ecstasia Sanders
- Â Angry Woman 1 episode, 2018
- Charles Zuckermann
- Â Big Guy 1 episode, 2018
- Corey Schmitt
- Â Buck 1 episode, 2018
- Joseph Allan Sutherland
- Â Jail Guard 1 episode, 2018
- Xander Hall
- Â Fort Collins Guard 1 episode, 2019
- Fraser Corbett
- Â EMT #2 1 episode, 2016
- Dustin MacDougall
- Â Shade 1 episode, 2016
- Harmony O'Reilly
- Â Gwen 1 episode, 2016
- Zak Mohamed
- Â Refugee 1 episode, 2016
- Matthew Smalley
- Â Travis 1 episode, 2018
- Kaiden Berge
- Â Attacker #1 1 episode, 2018
- Lori-Anne Jackson
- Â Nurse 1 episode, 2018
- Dave Jacox Sr.
- Â Loveland Prisoner 1 episode, 2019
- Mark Acheson
- Â Susan's Dad - Feral 1 episode, 2016
- Bill Butt
- Â Refugee 1 episode, 2016
- Tyson Larter
- Â Boy 1 episode, 2017
- Lauro David Chartrand-Del Valle
- Â Border Guard #1 1 episode, 2018
- Ellen Ewusie
- Â Grace 1 episode, 2016
- Terry Mullett
- Â Vampire Ghetto Guard 1 episode, 2016
- Paige Bateman
- Â Girl 1 episode, 2017
- Claire Smithies
- Â Kristina 1 episode, 2018
- Donald Heng
- Â Intern 1 episode, 2016
- Shayan Moallef
- Â Refugee 1 episode, 2016
- Darcy Hinds
- Â Boxing Opponent 1 episode, 2017
- Jason Bell
- Â Refugee 1 episode, 2016
- Aaron Hutchinson
- Â Tommy 1 episode, 2016
- Sam Duke
- Â Tyler 1 episode, 2017
- Kirby Morrow
- Â Gary 1 episode, 2016
- Jason Wingham
- Â Refugee 1 episode, 2016
- Shaz Mohsin
- Â Eden Survivor #1 1 episode, 2018
- Raquel Riskin
- Â Eden Survivor #2 1 episode, 2018
- Bethany Brown
- Â Grace 1 episode, 2016
- Seth Whittaker
- Â Burly Guard 1 episode, 2018
- Allan Luna
- Â Desk Officer 1 episode, 2019
- Robert Wellman
- Â Julius' Vampire (uncredited) 3 episodes, 2017
- Andrew Nadanyi
- Â Delta Vampire (uncredited) 3 episodes, 2021
- Richard David Lecoin
- Â Guard / ... (uncredited) 2 episodes, 2018-2019
- Kory Grim
- Â Vampire (uncredited) 1 episode, 2016
- Leah Barley
- Â Vampire (uncredited) 1 episode, 2016
- Marcio Moreno
- Â George (uncredited) 1 episode, 2017
- Derek Schnobb
- Â Throat Injury Patient (uncredited) 1 episode, 2017
- Ian Hawes
- Â Security Guard (uncredited) 1 episode, 2018
- Jane Kusak
- Â Vampire (uncredited) 1 episode, 2018
- Liam Raymond Dib
- Â Gladiator Prisoner (uncredited) 1 episode, 2019
- Hazel Atkins
- Â Human Sister (uncredited) 1 episode, 2019