A group of teenagers enroll in a prestigious high school, which turns out to be a devious trap designed to tempt the pupils to murder one another in order to graduate.

A group of 15 elite high school students are gathered at a very special, high class high school. To graduate from this high school essentially means you'll succeed in life, but graduating is very difficult. The school is presided over by a bear called Monokuma, and he explains to them that their graduation hinges around committing a murder. The only way to graduate is to kill one of your classmates and get away with it. If the other classmates discover the identity of the killer, the killer is the only one executed. However, if they fail to catch the killer, only the killer graduates and the others are annihilated. Which of the 15 will survive the bloodbath to come?—Anonymous

Naegi enters his new elite university of Peak's Hope and suddenly loses conscious, waking up later with a group of people. The aim is simple. The one who manages to kill a student without the others noticing gets to escape the university.—Pel Par

Based on the murder mystery video game Danganronpa: Trigger Happy Havoc, the show takes place at Hopes Peak Academy, a high school that accepts only the talented. When Neagi is enrolled he is unexpectedly knocked out and wakes up inside the school to meet his 14 other classmates none knowing that the only way to graduate is to get away with murder.