After Jane falls into a state of despair over her schizophrenia, she encounters new sources of love and life with surprising results.

This movie follows Jane (Sally Hawkins) who, after being left at the altar, had a breakdown spiraled into a chaotic episode of schizophrenia lasting 20 years, in which love (both real and imagined) and family relationships collide. Things change when she begins a darkly-comic romance with Mike (David Thewlis), a failed musician and fellow lost soul.