Three friends are on the verge of getting their video game financed when their benefactor is taken hostage by terrorists.
Alexxx, Darren, and Joel are three losers who work as maids at a hotel and all have problems. Alexxx is an impulsive and immature manchild. Darren constantly vapes to avoid the world around. Joel is a closeted gay man whose sexuality is obvious to everyone except himself. When word gets out that social media influencer Bae Awadi is coming to their hotel, the three try to pitch their game idea to him. But when terrorists arrive and take hostages, including Bae, the three must man up and save the day.
Three friends (Alexxx (Adam DeVine), Darren (Anders Holm), Joel (Blake Anderson)) work as housekeepers at a luxury hotel in Los Angeles. Alexxx has crazy business ideas like hot tutors for kids or $20/month plan for jeans rentals. He wants to make it big in life and not clean toilets for a living. Cassie (Aya Cash) is their supervisor at the hotel. Mitch (Daniel Stern) is the hotel manager.Cassie reports the trio's inappropriate behavior (yelling at guests and getting high) to Mitch, but he dismisses her saying "boys will be boys".
Mitch informs them that a huge party is headed to their hotel, and Mr. Ahmad (Jamie Demetriou) is the personal attache of the Bey of Tunisia Bae Awadi (Utkarsh Ambudkar). Alexxx sees this as a huge opportunity to pitch their business idea to the Bey and get funding. the friends agree to pitch Skintendo, a video game that they have been developing. When Alexxx leaves to get supplies, Darren and Joel discuss how they have been working on Skintendo without Alexxx.
Unknown to anyone, terrorists enter the building via the basement, impersonating the Bey's security team. The terrorists are led by Conrad (Neal McDonough), Erma (Rhona Mitra), hacker Donald (Sam Richardson). Conrad is working with Ahmad.Alexxx and his friends use the party in the evening to get close to Bae and pitch him the idea of Skintendo. Turns out the Bey is as crazy as the trio and likes the idea. Bey agrees to invest $200,000 over-ruling Ahmad's protests against the investment. As the boys leave with the check, Mitch takes the check from them and returns it to Ahmad.
Conrad enters with Erma and takes control of the party. Outside, Mitch fires the trio and as they leave, Erma enters and cuts off Mitch's penis (Mitch was hitting on her all evening). Alexxx comes back to confront Ahmad and Mitch and finds Erma standing over Mitch's dead body. He runs before Conrad and Erma can catch him. Donald enters the security room and takes control of the hotel building. All hotel staff are taken to the roof which is rigged with explosives.The trio find all exits guarded, and their phones were confiscated by Mitch earlier in the day. They hide inside a room, when 2 of the terrorists come conducting a room-to-room search. The trio hide waiting for the right moment to attack. The terrorists Rich (Steve Howey) and Jared (Mac Brandt) proceed to have gay sex in the room and are attacked. Rich is killed by Joel and an enraged Jared slips and splits his head open on the side table.
Conrad wants Bae to transfer $500 MM into an offshore account and presses him for the access codes, else he will kill his friends in the party one by one.Meanwhile The trio figure a plan to make a zip line across to a window cleaning bench at the next building. They rig an ironing board to carry them over. But then Rich (who was only injured by Joel), awakens, and attacks them and all 3 get onto the ironing board at the same time. Rich hangs off the window, while the board gets stuck halfway between the 2 buildings. The police arrive. As they try to enter from the front entrance, they are attacked and call for back up.
In the heat of the moment Joel and Darren reveal that they have been working on Skintendo without Alexxx. The trio get into a fight, the zip line breaks, and they crash into the security room, just when Donald was entering the access codes into the computer to finish the transfer. The computer is smashed. Donald gets tied up in the zip line and when rich climbs back up, the bed (to which the zip line was tied to, falls) falls and takes Donald down with it. Donald is dead.Joel figures that Donald's phone had Ahmad's number as the last dialed. Joel calls Ahmad and Bae sees that Conrad ignores that Ahmad has a phone (while all others were confiscated). This reveals to Bae that Ahmad was working with Conrad all along. Turns out Conrad was only working for Ahmad and Ahmad shoots him dead.
Alexxx speaks to Ahmad and the trio also confirm that Ahmad is the ringmaster of the hostage situation. Ahmad releases a video to the US govt asking for $500 MM ransom for 106 hostage and a helicopter to fly out of the US. Any attempt to attack the building will trigger the collar explosive around the hostage's neck. He promises to shoot 1 hostage every 15 mins.The trio plan to use all the Salvia drugs in Alexxx's room to stone the hostages and their gunners in the conference room and take control over.
They head to the AC ducts to plug their device in, but Erma tracks them down. She shoots the device, but the trip escape and Erma inhales a huge amount of Salvia. The trio team up to fight off one of her men and kill him in the hotel kitchen.Meanwhile Ahmad kills Bey's dog and makes hostages fight each other to the death every 15 mins.The trio are tracked down by Rich, who holds them at gunpoint. Rich ties the trio down in the spa room and starts torturing them, but they gang up on him and shoot him dead.
Darren and Joel team up to make a Skintendo out of Rich's corpse. Basically, they rig the outside of his body with electronic controllers, which can be manipulated to mimic orders given via an iPad. They get Rich to enter the conference room and take out a few bad guys, before the batteries overheat and Rich blows up into pieces.The trio follow Rich and corner Ahmad at gunpoint. But that's when Erma recovers and enters the conference room. Ahmad escapes with the money (paid by the Govt), but Joel uses the moment to reveal he is gay and proceeds to bitch slap Erma. Erma has the upper hand the entire fight, but then Mitch enters and throws his dick at Erma, distracting her, giving Joel the opportunity to impale her on a piece of wood.
The guys head to the roof and convince Ahmad to exchange Bey for the bags of money he left behind. Ahmad agrees and takes off with the money. But the guys had put all the collar explosives in the money bags and when the hostages leave the hotel, they trigger the bombs, which explode inside the helicopter, killing Ahmad.Bey refuses to write the guys another checks for Skintendo and he admits that he only wrote the first check to anger Ahmad. But then Mark Cuban steps up. Apparently, he was a hostage. He is not interested in the Skintendo but offers to buy the trio's story and turn it into a video game.The video game is "Game Over, Man". 2 years later, the trio are rich and having a party on a yacht. But unknown to them, they are being pursued by Somali pirates.
