In a futuristic metropolis full of super-powered students, Kamijo, Index and their allies use sorcery and science to keep Arisa, a level 0 girl, safe.

On the day Touma Kamijou and Index see Academy City's space elevator, Endymion in the distance, they meet a Level 0 girl with an amazing singing voice, Arisa Meigo. As the three enjoy their time together after school, magic-user Stiyl Magnus suddenly attacks them. His target: Arisa. Why would a girl from the science side be targeted by someone from the magic side, Touma wonders. In the chaos of Stiyl's attack, he tells Touma, Index and Arisa that she might cause a war between the magic side and the science side.—Anime News Network