Sho and Tetsurou find an alien artifact that bonds with Sho, transforming him into the Guyver. He must battle the evil Chronos corporation and their Zoanoids, who want to recapture the Guyver.

Sho and his friend Tetsurou stumble upon an odd alien artifact while walking through the woods. Then, the alien artifact breaks free of its metallic bonds and enters Sho's body, turning him into the Guyver. With this new power, Sho must do battle with the evil Chronos corporation and their genetically enhanced Zoanoids, who seek to get the Guyver back into their labs. No one close to Sho is safe from Chronos. He must fight.