The Macahans, a family from Virginia, headed by Zeb Macahan, travel across the country to pioneer a new land and a new home in the American West.

Episodes revolving around the Macahan family as they try to fulfill their dream of going to Oregon. They run into many setbacks along the way and are forced to delay their move many times as a result. Common wild west themes and characters abound, such as Native Americans and crazy mountain men.—Anonymous

In 1865, the Macahans are heading west from Virginia to Oregon. Mrs. Kate Macahan is waiting with her children Laura, Jessie and Josh on a farm they have built for her husband and her oldest son Luke to return from the civil war. Luke comes back when he defects from the army with the news that their father is dead. An army officer comes to the farm to arrest Luke but luckily their uncle Zeb, a frontiersman, saves the day. But Luke must leave them and hides among a Simonite community. Zeb also leaves for the mountains to find an old friend who is at war with the Indians. How can the others deal with the Indian war that threatens to break out around the Macahan farm?—Mattias Thuresson

Zeb Macahan takes in his orphaned nieces and nephews after their parents are killed and raises them with the help of their aunt Molly Culhane. The kids are Luke, Laura, Josh and Jessie. Oldest brother Luke is a fugitive from the law accused of murder. He deserted the Army after killing three men in self-defense and must find a way to prove his innocence. The show deals with Indians, nature, and other expected problems of frontier life.—Anonymous