The Anti-Monitor (the Monitor's evil counterpart) is released into the DC Multiverse and begins to destroy the different Earths that compose it. The Monitor attempts to recruit heroes from across the Multiverse to fight back.

An endless army of shadow demons bent on the destruction of all reality swarms over our world and all parallel Earths. The only thing opposing them is the mightiest team of metahumans ever assembled. But not even the combined power of Superman, Batman, Wonder Woman, Green Lantern and all their fellow superheroes can slow down the onslaught of this invincible horde. What mysterious force is driving them? And how do the long-buried secrets of the Monitor and Supergirl threaten to crush our last defense?—Jakkepoes