Lupin investigates the kidnapping of a former love in Italy, and is drawn into a game with an unknown enemy.

Italian millionaire and celebrity Rebecca Rosselini, who married the legendary thief Lupin III and still carries his name, is kidnapped. But when Lupin arrives in Italy to rescue her, he finds himself issued a challenge by the Masked Count: find the inheritance of the Count of Cagliostro. To complicate matters, Lupin's nemesis Inspector Zenigata arrives in Italy to arrest Lupin, as well as MI6 Agent Nyx who is after the Masked Count as well. With all the players arrived, the Italian Game begins, but who will be the winner?