When strange anomalies start to appear all over England, Professor Cutter and his team must track down and capture all sorts of dangerous prehistoric creatures from Earth's distant past and near future.

In 1998, Professor Nick Cutter's wife Helen disappeared through a rupture in time known as an anomaly. Eight years later anomalies to different points in Earth's history are beginning to appear all over London, bringing with them dangerous prehistoric creatures. To combat the anomaly threat, government officials James Lester and Claudia Brown form a research team led by Professor Cutter (in later series, Danny Quinn and Matt Anderson) with the aim of capturing the creatures and sending them back to their own time.