The sequel series to He-Man, taking place 10,000 years into the future. Prince Adam is brought from the past to protect the Planet Primus from the evil mutants led by Floog and Skeletor.

He-Man is the legendary "Most Powerful in the Universe" and the mighty warrior of the planet Eternia and defender of the mysterious Castle Greyskull. With his special powers and with his weapon, The Sword of Greyskull, He-Man fought the evil Skeletor who bid to rule Eternia and discover the secrets of Greyskull. He-Man has been summoned to the planet "Primus", a world under threat from a band of evil mutants from the nearby planet "Denebria". But Skeletor has joined forces with the mutants in his goal of universal conquest. With help from his new companions: The Galactic Guardians, a loyal squadron of soldiers led by Captain Hydron and Lt. Flipshot, Teenage girl Drissi and her brother Caz and Darius, head of the galactic council. He-Man sets out to defend Primus from Skeletor and the mutants.—Daniel Williamson