Telepathic waitress Sookie Stackhouse encounters a strange new supernatural world when she meets the mysterious Bill Compton, a southern Louisiana gentleman and vampire.

Set in modern times, vampires roam the Earth and are humans' mortal enemies. However, a substitute has been found for human blood, a substitute that vampires can consume with the same effect as human blood. This is True Blood. Now humans and vampires can co-exist in harmony, and even form relationships. But there will always be rogue elements on both sides ready to exploit the uneasy truce.—grantss

Vampires have been around for centuries, but they have only recently "come out of the coffin" and entered mainstream life. Sookie Stackhouse, a telepathic waitress in a small Louisiana town, finds her world turned upside down upon meeting her first vampire, Bill, and falling in love with him. The series follows Sookie through many adventures with humans, vampires, and, eventually, other supernatural beings. She discovers that the world and the people in it are not always as they seem.

The series follows Sookie Stackhouse (Anna Paquin), a barmaid living in Louisiana who can read people's minds, and how her life is turned upside down when the vampire Bill Compton (Stephen Moyer), walks into her place of employment two years after vampires "came out of the coffin" on national television.—ahmetkozan