Fangface and friends try to stop a group of modern day pirates from stealing an Aztec treasure. If the treasure is stolen, an ancient mummy will awaken and destroy the island.
When the Fangface friends are accidentally launched into space on the space shuttle, they dock at an orbiting space station. On board, they encounter an alien being who is stealing the minds of the scientists.
A crooked swami hypnotizes "The World's Strongest Teen" to get him to commit crimes. He happens to be a friend of Fangface and the gang and things get complicated when Biff is hypnotized as well and turns on them.
While travelling in the Amazon jungle, the gang meets a Princess who has been banished by her tribe of Amazon Women Warriors. They try to help her regain her throne.
The gang wins a contest and the prize is an invitation to a costume party held by a famous actress. A sorceress tries to sacrifice the actress to become the Bride of the Gargoyle.
A scientist creates a formula that can turn him into a Werewolf. He commits crimes and Fangface is blamed. Things get interesting when Pugsey swallows the formula and becomes a Werewolf himself.
The Cobra Queen kidnaps and then impersonates the world's most wealthy woman in an effort to get her entire fortune signed over to the Cobra Queen. The gang witnesses the kidnapping and tries to help.
