A mutant named Jacob is Rejected from Professor Ex's School for Ex Humans. He receives an invitation to join another group of mutants called "The Reject-Men" He quickly finds out why these mutants were rejected from the school.
Carl begins training the Reject-Men in combat, while Gill works on figuring out how they can control their powers. All the while, Professor Ex and the Ex-Men, search for the Reject-Men to ask them to lay down their arms. During this feud, we are also introduced to a new group of mutants.
Jaq makes her presence known. Gill and Jacob fight for position and the hearts of the Reject-Men. Meanwhile Carl finds an ancient power source which could help give the Reject-Men control of their powers.
Jaq sends a message to the people of Boise, Idaho that she will carry out another attack. This time, she leaves a riddle as clue to where her bomb will be. With Gill gone, it falls to Jacob to come up with a plan to stop Jaq. The Reject men carry out their plan, which works, but one of the members is captured.
The Reject-Men try and figure out how to move forward after the tragedy. Meanwhile Gill arrives in El Pollo, Mexico to search for the fabled, ancient, Aztec power source.
