A double homicide in upstate New York leads detectives on a cross-country investigation to piece together a case with a surprising suspect at the center; the architect behind the murders is interviewed;
The murder of a young businessman in Old San Juan, Puerto Rico marks the start of a 15-year hunt and the FBI begins an international game of cat and mouse to find the killer. Natalie Morales reports.
A woman is found murdered in her car outside of her apartment. Solving this mystery would take not just years, but also involve at least one more murder, her boyfriend's twin brother.
A California woman eludes police after both of her husbands are found murdered nearly 20 years apart. Until fate catches up with her. Keith Morrison reports.
A Pennsylvania father has a premonition that he'll be murdered and the case will go unsolved. Weeks later, he is found stabbed to death. But would the case go unsolved?
A nurse is murdered in what police say is a burglary gone wrong. The case goes cold for over two decades, until a killer is identified the last person anyone would suspect. Josh Mankiewicz reports.
Ben Oxley is shot in the head in his own bed; no one else in the house was hurt, including his wife Melissa Oxley, who was sleeping beside him. Keith Morrison reports.
A Colorado woman vanishes. No crime scene. No evidence. No body. Would a dark secret about her marriage lead to clues that solve the mystery of her disappearance? Dennis Murphy reports.
After Lisa Ziegert is abducted during her evening shift at a gift shop, local detectives, state police and the FBI work relentlessly to find her and solve the case after decades.
A glimpse of a sobbing woman lighting black candles is seared into a 9-year-old girl's memory. Decades later, that girl reveals what she saw, reopening the investigation of the unsolved murder of an Iowa bartender. Keith Morrison reports.
Family members and the lead investigators, who cracked the Kelsey Berreth case, speak about the murder of Colorado mother Kelsey, whose disappearance made national headlines after she was last seen grocery shopping on Thanksgiving 2018.
Where are the children? An investigation into the case of two missing Idaho children are making national headlines. The trail leads Keith Morrison to Hawaii in search of their mother and her new husband;
When grad student Katie Sepich is murdered, her killer leaves behind his DNA. The Sepich family fights for both justice and to get the law on DNA collection changed. Josh Mankiewicz reports.
Karl Karlsen's wife dies in a house fire. Then his prized horses die in a fire. And his son dies in an apparent accident. How can one man can be so unlucky? Andrea Canning reports.
A fugitive steals millions of dollars by conning numerous women and businesses over 25 years. Will law enforcement finally be able to catch him? Andrea Canning reports.
A coroner arrives at the scene of a car accident to find his friend, Judy Orr Baldwin, deceased. He begins to think her death looks suspicious after he notices some unusual markings on her face. Was it an accident, or something far more sinister? Andrea Canning reportS.
Three siblings' lives change when their father is taken hostage in an orchestrated abduction. For the first time, they open up to Keith Morrison about their ordeal and its stunning conclusion.
Brittany Stork's decades-long quest to find out more about her mother's mysterious death leads to a dramatic courtroom decision; the man at the center of the case tells his side of the story;
When Dr. Teresa Sievers is found murdered in her kitchen, detectives struggle to find any leads until an unexpected tip changes everything. For the first time on national TV, the woman who helped investigators speaks out. Dennis Murphy reports.
A former FBI agent is murdered at his house, and as police dig into his past, they begin to think the key to solving the mystery might be quite close to home. Josh Mankiewicz reports.
College student Jesse James Valencia, age 23, is murdered on 6/5/2004 in Columbia, MO. Police investigate a member of their own department. Ex-cop Steven Rios is convicted of the murder and is sentenced to life imprisonment without parole.
A former hairdresser who became a police detective takes the death of a 15 year old girl whose body was found on a scenic Utah river personal, working the case for years and in honor of a fallen fellow officer.
Exclusive interviews with close family members of Lori Vallow, the Idaho mother charged with deserting her children, Tylee and JJ, who have not been seen since September. Keith Morrison reports.
The story of Rebecca Musser vs. FLDS leader and notorious FBI fugitive Warren Jeffs. Rebecca opens up to Keith Morrison about life in the church and why she decided to leave the denomination.
The youngest sister of a large, tight-knit family on Long Island, vanishes without a trace. The two-hour broadcast features the latest in the case, as well as extended interviews with key players in the investigation. Andrea Canning reports
When Bryan Rein, a young Montana veterinarian, is found dead at his home with a gun nearby, police quickly discover there is more to the case than meets the eye. Keith Morrison reports.
A successful businesswoman and mother of three is found shot in her office; the investigation into her death leaves a family divided. Keith Morrison reports.
An in-depth and comprehensive look at whether the COVID-19 pandemic, that tore through the United States, could have been contained or slowed had government agencies responded differently;
An interview with the former best friend of Lori Vallow, the Idaho mom charged in connection with the disappearance of her two children, whose remains were recently discovered;
Sgt. Kenneth Ventresca, lead investigator in the case of missing Connecticut mother Jennifer Dulos, tells Dateline NBC that the police is still "actively" investigating her disappearance;
After a young Army veteran disappears, detectives uncover a cryptic 911 call, placed 11 days before she went missing, which exposes a twisted story --- and the truth;
Oscar Pistorius shoots and kill his girlfriend, just eight months after competing in the London Olympics, telling police that he believed that she was an intruder and he was acting in self-defense;
Nearly 40 years after an Iowa high school senior is found stabbed to death, in her car, after visiting the mall before Christmas, investigators identify the killer.
A man calls 911 to report that his pregnant wife has died by suicide; the case is closed until a suspicious house fire, 24 years later, leads police to question what really happened that day;
