The Clampetts are concerned Mr. Drysdale is worrying too much about their money. When Jethro misunderstands and believes Britain's queen is broke, the family heads to their English castle to help her out.
Heading to England Jethro smuggles Ellie's turkey buzzard on the plane upsetting Mr. Drysdale and a fellow passenger. After landing they try to meet with the Queen to give her their 80 million dollars. Their butler Faversham tries to clear things up.
The Clampetts fly to London to give the Queen the deed to Canada they purchased. Waiting for an appointment with the Queen they stay at Clampett castle, where Granny is thinks they are at war with a neighboring castle.
In an attempt to get the Clampetts to move back to California, Mr. Drysdale tells Granny about the spirit of Lady Clementine. Her husband was murdered in the Clampett castle. Lady Clementine's ghost is going to return to seek revenge on the person who killed her husband; her little old grandmother.
Jethro and Elly dress up in Bonnie and Clyde costumes and end up scaring Mr. Drysdale; to get back at them, Mr. Drysdale dresses up as a bank robber but gets caught.
Jethro wants a new identity with replacement of their old truck with a modern hot rod. Granny wants to stay with the old truck. To prove how good the old truck is Granny races Jethro in his hot rod.
The Clampetts return to Hooterville to celebrate Christmas. Mr. Drysdale, convinced that Mr. Clampett intends to move all of his money to Mr. Drucker's bank, drives to Hooterville to stop him.
Mr. Drysdale follows the Clampetts and Miss Jane to Hooterville where they are spending Christmas. He takes Ellie's bear Fairchild with him and gets himself thrown in jail in a little town called Ripley. Sam Drucker shows up to help.
Mr. Drysdale is sick and Dr. Granny springs into action with a chimp as a nurse. But Ellie's bear Fairchild has taken a liking to granny's "flu" remedy. During this, Mrs. Drysdale tries to impress society matron Mrs. Van Ransohoff.
Jethro's new plan is to become a big-time talent agent, and his first action is hiring beautiful Babs and Bunny. Cousin Roy, told he has musical gifts, arrives but Jethro refuses to accept him as a client which upsets the other Clampetts.
Jethro agrees to take on cousin Roy as a client but then he changes everything that made the banjo player likeable. Granny, Jed, and Ellie are dismayed but a hit record happens in spite of Jethro.
Jethro is evicted because his 50-cent allowance won't cover the rent. The other Clampetts take over the space: Granny will cut hair or pull teeth, Jed will sharpen tools and whittle things, and Elly is the pretty receptionist.
With the Clampetts established "in business" in Jethro's vacated office space, a building inspector visits to find out about their business operations on the 5th floor.
Granny provides Homer Cratchit with a baldness cure which makes the other employees curious about what's going on on the 5th floor. One secretary sets her sights on marrying Jed.
Jethro meets Mrs. Drysdale's guru and decides he wants to be one also. Granny thinks it's all nonsense but when she tries to put a stop to it the followers find her common sense inspiring and make her the head guru.
The Drysdales now jog, so the banker can get the account of Jason Detweiler, head of a running club. The Clampetts don't understand the concept, leading to misunderstandings, then Elly and Jethro become enthusiastic.
Famous singer Pat Boone is in the neighborhood and smells Granny's cooking. He wanders into their backyard and the Clampetts befriend him, thinking he's a hill country man down on his luck.
