Just as the title implies, Mario gets his reproductive system caught in the doorway to his house, and after calling Luigi on his cell phone, Luigi, along with SMG4, Bob, and Shroomy arrive to help him out of the doorway.
After Mario fails to persuade his friends to join a school club of his own design, Meggy tells Mario that they will join, but only if he lets the others decide what kind of club it will be.
In his never-ending quest to reach Meme Lord status, a sleep-deprived SMG4 managed to create the Ultimate Meme, storing it in a USB Flash Drive and planning to use it to control the Internet.
SMG3 has gathered his team from SMG4: I Can't Believe It's Not SMG4! (2020) again, including Mario. This time, SMG3 has put together a plan to steal Susan's remote from her in order to rebuild his destroyed production studio. Will the heist succeed?
Mario's friends must stop their past selves from never meeting Mario. Can they prevent their destinies from never occurring? Or will they learn what it is like to lose?
The fans controlled the episode this time using the most upvoted Reddit posts. Fans were given one topic, and they had to follow it until the end of the episode.