Daphne complains about her mother's pushiness in planning her wedding. Frasier makes a Freudian slip that leads her to think that he and Martin are offering to pay for her wedding, which she joyfully accepts.
Frasier returns home and finds a strange woman in a towel using the phone. It soon turns out that her name is Regan, she recently moved in next door, and Martin rescued her when she accidentally locked herself out.
The rift between Martin and his sons' tastes is bridged when they find they are all fans of "The Antique Roadshow." The boys have a great time watching it on TV, and when the Roadshow comes to Seattle, they all go.
A minor fender-bender sends Frasier to the hospital a slight bloody nose. While waiting, Niles hears the name of Maris's plastic surgeon, Mel Karnofsky, whom he decides to confront about a billing error.
Lilith and Frederick come for Thanksgiving dinner with the Cranes. Frederick manoeuvers Frasier and Lilith into spending an evening together, and they begin to suspect that he is trying to get them back together.
On his birthday, Frasier is seized with crippling back pain. Niles wonders if he's stressed, and while recovering at home, Frasier muses aloud about why he's unhappy.
Daphne is unsure how to deal with Niles's feelings for her. Roz assures her there's nothing to worry about: Niles has a girlfriend now, and Daphne is engaged to Donny.
Frasier recalls his millennial New Year's Eve as he, Niles and Martin rumble down the back roads in Martin's bulky Winnebago bound for the wine club's festive get-together in Idaho.
At Cafe Nervosa, Frasier runs into his unrequited high school crush and former prom queen, Lorna Lynley. The courtship gives Frasier a chance to live up the high school glory days that he never had.
When Roz takes a vacation, Frasier hires Mary, a producer fresh out of of training, to fill in for the week. Soon, Mary starts taking over Frasier's show.
Frasier hosts an informal brunch in order to acquaint himself with Niles' lady love Mel, but little does he know that the plastic surgeon is a manipulative schemer who slickly wants to push Niles out in front of his brother.
Frasier and Roz share a room at a broadcasting conference, which is notorious for being a meet market. However, both strikeout miserably and return to the room dejected.
Frasier's show is pulled off the air for a week, supposedly to give a new talk show a try, but Frasier has figured out the real reason: leverage against him in his contract negotiations with the station.
Frasier learns that comely neighbor Regan Shaw has recently become available again, but is shy about approaching her because his previous encounters with her resulted in him looking foolish.
In a session with her therapist, Daphne recalls (through flashbacks) a series of unfortunate events following the surprise shower that her fiancé, Donny, threw for her.