Elizabeth Vargas is interviewed by Diane Sawyer, in the Season 40 premiere, about her secret struggle with alcohol and anxiety, as revealed in her memoir, "Between Breaths".
Police provide correspondent Ryan Smith access to their investigation into the brutal murder of a University of North Carolina sophomore in September 2012, Included: a DNA generated composite of what the alleged killer may look like; interviews with the victim's parents and her siblings.
University of Virginia's former Associate Dean of Students Nicole Eramo talks about the Rolling Stone article, detailing the alleged gang rape of a University of Virginia student at a frat party.
U.S. authorities scrutinize a supposed miracle cure for autism that a fringe church is promoting; employees faking injuries to receive disability; an American woman convinces people that she is a descendant of French nobility.
A look at the life of Donald Trump and how he captured the presidency, featuring interviews with his family, longtime friends and campaign manager, Kellyanne Conway.
Journalist Gretchen Carlson speaks out about the sexual harassment she's experienced throughout her life; a former Wall Street trader talks about the sexist atmosphere he observed at work; the lengths that people will go to prove harassment claims.
A profile of Owen Suskind, an autistic young man who learned to communicate with the help of animated movies and was the focus of the documentary Life, Animated (2016).
A conservation with Keith Papini, husband of Sherri, the California mom who disappeared on Nov. 2, 2016, and was later found bound and injured 150 miles from her home.
A man who served on the grand jury that voted to indict John Ramsey and Patsy Ramsey in the 1996 murder of their daughter, JonBenét Ramsey, believes he knows who committed the crime.
Ex-members of the Church of Scientology who crusade against it; actress Leah Remini discusses her fight against the Church of Scientology and her goal of making it lose its tax exemption status.
Profiles of working individuals and families across America, who are struggling to stay in the middle class; issues of dwindling job opportunities, income inequality and community solutions are explained.
A man, found adrift at sea in a life raft, claims his mother disappeared when their boat sank during an ill-fated fishing trip the two had embarked on.
Playboy model and reality TV star Anna Nicole Smith is remembered, 10 years after her sudden death; new information about her glamorous and mysterious life is revealed through conversations with Larry Birkhead and others who were close to her.
The ex-wife of Justin Ross Harris -- who is currently serving a life sentence for leaving their son in a hot car, resulting in the child's death -- talks about the incident.
A 16-year-old gay teen, whose mother sent him to a series of Christian-run youth camps that practice so-called "gay-conversion therapy", talks about his experience.
After running out of gas while driving alone in the desert, a young woman survives five days with limited food and water, before being found by a rescue team.
A Canadian woman, who served time for cat-fishing professional basketball player Chris Anderson and a 17-year-old girl who had a social media presence, discusses the reasons behind her scheme.
Two years after the interview, during which she announced she was transitioning to female, Caitlyn Jenner reconvenes with Diane Sawyer to talk about the realities of her life.
A Tennessee high school teacher, accused of kidnapping his 15-year-old student, causes a 38-day manhunt that ends with the two being found in northern California; interviews with people close to the case.
Computer programmer and businessman John McAfee discusses being named a person of interest in the murder of his neighbor and the resulting tumult. He also discusses what his life is like today.
An international investigation into Otto Warmbier's 17-month imprisonment in North Korea, and his death, which occurred less than a week after he was brought back to the United State in a state of unresponsive wakefulness.
An exploration of the nationwide crisis of road rage and how incidents can quickly become dangerous; traveling across the country with the Colorado State Patrol.
Footage of U.S. border officers accused of encouraging a 16-year-old to drink a dangerous liquid to prove he's not a smuggler; cases of border agents and officers being accused of abusing those crossing the border.
A jury convicts a former FBI agent and his daughter of second-degree murder in the death of the daughter's husband; pretrial interviews with the defendants, crime-scene evidence and audio documentation of marital trouble.
Looking at the increased activity of white nationalists and white supremacist groups, and the anarchism and anti-fascist groups that have formed on the far left to combat them.
A reality-TV executive receives a rare hand transplant, after losing limbs due to gangrene, related to the uncommon and aggressive autoimmune disease that almost killed him.