Prof. Oak sends the gang on an errand to the Orange Islands to retrieve a mysterious pokeball from Prof. Ivy. But the gang pass through the woods and find an army of Spearow, lead by Fearow, bullying the Pidgey and Pidgeotto.
After waking up from Jigglypuff's song, Ash and Misty find themselves deeper in the Orange Islands. Finding an abused Lapras, they try to help it find its trust in humans again.
With Lapras and Tracy as their new traveling companions, Ash, Misty, and Pikachu head for Mikan Island to challenge Sissy, the first of the four Orange League gym leaders.
Ash and his crew reach Mandarin city, where mysterious occurrences of Pokémon turning against their own trainers happen. Inevitably Pikachu turns against Ash and disappears in the commotion of a volt-rob's explosion. Will Ash find Pikachu and solve this mystery?
Ash finds a bottled letter floating in the sea that mentions a mysterious crystal Onix. In the hopes of seeing this one of a kind Pokémon, Ash helps a young girl and his brother find some inspiration by searching for the Onix.
After getting caught in a whirlpool, Ash and his crew get washed up at Pinkan island, where the Pokémon are pink due to the vegetation there. They help Officer Jenny in stopping Team Rocket from poaching the Pokémon from this Pokémon reserve.
A pokémon fossil is tracked back to a deserted island where an archaeological team is about to investigate the secret of its origin, but a prophecy has it, that the island isn't to be disturbed.
Misty meets another trainer who also is an expert on water Pokémon. The new trainer notices signs that Misty's Psyduck may be ready to evolve. As the two prepare for a Pokémon battle, a Golduck springs from the water and battles for Misty.
While sailing between small islands, the group encounters an extremely busy Nurse Joy. She tells the group that she travels from island to island helping sick and injured Pokémon, and invites our heroes to travel with her.
While Ash and friends are still discovering new islands, they come upon the seven Grapefruit Islands. When it looks like thieves are stealing the grapefruit, Ash, Tracey and Misty volunteer to help catch them.
Ash, Tracey, and Misty find more excitement than they bargain for when they reach their next destination. Divers have recovered an Orange League Championship trophy that dates back over three hundred years.
Team Rocket has engine trouble and lands on an island where the natives are waiting for the Great Meowth of Bounty to arrive and fulfill an ancient prophesy.
After Team Rocket tries once again to steal Pikachu, Ash and company fall into the Trovitopolis Sewer System, where a monster has been terrorizing the town.
Ash faces Rudy, the Orange League gym leader of Trovita Island. But Rudy has a thing for Misty. Will Misty be able to decide who to support during the match?
In a fight with a kid, Ash accidentally breaks Snorlax's poke-ball. To repair the poke-ball, they reach a Pokémon center where they help them retrieve the long awaited Pokémon food from team Rocket.
Ash has his battle with the final Orange League gym leader, as a two-on-two battle. He chooses Charizard and Pikachu. Finally, Charizard is beginning to listen to Ash.
Ash, Tracey and Jessie accidentally breathe in vile-plume's stun spore. Misty makes a new friend in the lakes who helps her find the weed needed to cure Ash and Tracey.
After winning the Orange League, Ash and friends start heading back toward Pallet Town when they encounter a group of Lapras, one of whom is Lapras's mother.
The gang arrives on Hamlin Island, which has a ferry that goes to Pallet Town. The residents have deserted the town, however, because it's been taken over by Electrode.
Ash and his friends finally arrive at Pallet Town, where they're surprised to see Brock waiting for them. Tracey is excited to meet Professor Oak, so they visit Professor Oak's lab.
